Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.65 |
| ▸ | THRB | P10828 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8848678 | 0.91 | RAB9A (0.53) | RAB9AL3MBTL1NPC1THRBSMN1; SMN2 | |
| SCHEMBL8848545 | 0.91 | RAB9A (0.52) | RAB9AL3MBTL1NPC1THRBSMN1; SMN2 | |
| SCHEMBL8848771 | 0.90 | RAB9A (0.52) | RAB9AL3MBTL1NPC1THRBSMN1; SMN2 | |
| SCHEMBL8848405 | 0.89 | NPC1 (0.64) | RAB9AL3MBTL1NPC1THRBSMN1; SMN2 | |
| SCHEMBL8848732 | 0.89 | RAB9A (0.51) | RAB9AL3MBTL1NPC1THRBSMN1; SMN2 | |
| SCHEMBL8848839 | 0.88 | HDAC6 (0.60) | RAB9AL3MBTL1NPC1THRBSMN1; SMN2 | |
| SCHEMBL8848741 | 0.88 | MAOB (0.52) | RAB9AL3MBTL1NPC1MAOBELANE | |
| SCHEMBL8848554 | 0.88 | RAB9A (0.50) | RAB9AL3MBTL1NPC1THRBSMN1; SMN2 | |
| SCHEMBL8849417 | 0.88 | MEN1 (0.61) | RAB9AL3MBTL1NPC1SMN1; SMN2HDAC6 | |
| SCHEMBL8848821 | 0.87 | HDAC6 (0.54) | RAB9AL3MBTL1NPC1THRBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602161-A | ELASTASE INHIBITORS; PREVENTING AND TREATING EMPHYSEMA, ENDOTOXIN-INDUCED LUNG DISORDERS | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 1997-02-11 | — | — | US | disclosed |
| EP-0676396-A1 | Tetrazolylphenyl pivalate derivatives and medicinal composition containing the same as effective component | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1995-10-11 | — | — | EP | disclosed |