Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL8848766 | 1.00 | ALDH1A1 (0.44) | ALDH1A1PTGS2CYP4F2CYP4A11CYP1A2 | |
| Bromide SCHEMBL8848908 | 0.87 | CA12 (0.41) | ALDH1A1KMT2AMEN1 | |
| Bromide SCHEMBL8849383 | 0.87 | ALDH1A1 (0.42) | ALDH1A1PTGS2CYP4F2CYP4A11CYP1A2 | |
| Bromide SCHEMBL5279859 | 0.87 | CA12 (0.41) | ALDH1A1KMT2AMEN1 | |
| Bromide SCHEMBL5279218 | 0.84 | KMT2A (0.44) | ALDH1A1PTGS2CYP4F2CYP4A11CYP1A2 | |
| SCHEMBL1899174 | 0.78 | KMT2A (0.38) | ALDH1A1PTGS2KMT2AMEN1 | |
| SCHEMBL9591167 | 0.78 | KMT2A (0.38) | ALDH1A1PTGS2KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL11387894 | 0.76 | KMT2A (0.37) | ALDH1A1PTGS2KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL11387891 | 0.76 | KMT2A (0.37) | ALDH1A1PTGS2KMT2AMEN1 | |
| Bromide SCHEMBL5391070 | 0.74 | KMT2A (0.43) | ALDH1A1PTGS2CYP4F2CYP4A11CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555070-B1 | Photocurable compositions | SERICOL LTD (GB) | 1997-04-16 | — | — | EP | disclosed |
| US-5332651-A | Screen printing | SERICOL LIMITED (GB) | 1994-07-26 | — | — | US | disclosed |
| EP-0555070-A1 | Photocurable compositions | SERICOL LIMITED (GB) | 1993-08-11 | — | — | EP | disclosed |