Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1904000 | 0.92 | GGPS1 (0.47) | GGPS1TRPA1CYP19A1AKR1C3AKR1C2 | |
| SCHEMBL27314752 | 0.84 | GGPS1 (0.43) | GGPS1TRPA1CYP19A1AKR1C3AKR1C2 | |
| SCHEMBL13189961 | 0.82 | GGPS1 (0.42) | GGPS1TRPA1CYP19A1AKR1C3AKR1C2 | |
| SCHEMBL9454043 | 0.82 | GGPS1 (0.42) | GGPS1TSHRTRPA1CYP19A1AKR1C3 | |
| SCHEMBL27346370 | 0.82 | NOS1 (0.51) | GGPS1ENPP2NOS3NOS1NOS2 | |
| SCHEMBL8848832 | 0.80 | TAAR1 (0.47) | GGPS1AKR1C3AKR1C2 | |
| SCHEMBL5046544 | 0.79 | PRSS1 (0.47) | PRSS1PRSS2PRSS3ENPP2TSHR | |
| SCHEMBL2812304 | 0.79 | TRPA1 (0.48) | PRSS1PRSS2PRSS3GGPS1TSHR | |
| SCHEMBL3800542 | 0.78 | AKR1C3 (0.39) | PRSS1PRSS2PRSS3GGPS1CYP19A1 | |
| SCHEMBL2229094 | 0.78 | MAOB (0.47) | PRSS1PRSS2PRSS3GGPS1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240612-A1 | Prenylated Bisphosphonates as Anti-tuberculosis Agents | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2010-09-23 | — | — | US | disclosed |
| US-5234946-A | Anticholesterol, antilipemic | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-08-10 | — | — | US | disclosed |
| EP-0318860-B1 | SUBSTITUTED ALKYLAMINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-06-16 | — | — | EP | disclosed |
| EP-0318860-A2 | Substituted alkylamine derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-06-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240612-A1 | Prenylated Bisphosphonates as Anti-tuberculosis Agents | GGPS1, FDPS, DCTPP1 | PRSS1 2235/4885PRSS2 4193/4885PRSS3 3871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.