Ethylene Glycol

Ethylene Glycol

SCHEMBL8848865

C=CN(C=O)CCC(=O)O.C=CN(C=O)CCC(=O)O.OCCO

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CAMK2A Q9UQM7 1/20 0.34
ABCC4 O15439 1/20 0.32
MAPT P10636 1/20 0.32
GPR84 Q9NQS5 1/20 0.32
FFAR1 O14842 1/20 0.32
FFAR4 Q5NUL3 1/20 0.32
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
BLM P54132 1/20 0.31
SLC6A3 Q01959 1/20 0.31
MEN1 O00255 1/20 0.31
CYP2D6 P10635 1/20 0.31
TSHR P16473 1/20 0.31
NFKB1 P19838 1/20 0.31
CYP2C19 P33261 1/20 0.31
KMT2A Q03164 1/20 0.31
LMNA P02545 1/20 0.31
ALKBH5 Q6P6C2 1/20 0.31
SUCNR1 Q9BXA5 1/20 0.31
EGLN1 Q9GZT9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2196802 0.94 MAPT (0.35) ABCC4MAPTSLC6A2SLC6A4BLM
1,4-Butanediol SCHEMBL8848756 0.92 GPR84 (0.43) CAMK2AABCC4MAPTGPR84FFAR1
1,6-Hexanediol SCHEMBL8848956 0.91 GPR84 (0.47) CAMK2AABCC4MAPTGPR84FFAR1
SCHEMBL8849194 0.81
SCHEMBL2179850 0.79
SCHEMBL2367372 0.78
SCHEMBL8591530 0.78 CNR1 (0.38) MAPTBLMMEN1TSHRKMT2A
SCHEMBL8768106 0.78 CYP1A2 (0.39)
SCHEMBL8595996 0.77 ALDH1A1 (0.34)
SCHEMBL2178498 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0779272-A1 N-Vinylformamidopropionates, process for their synthesis and their use as chain extenders and crosslinking agents AIR PRODUCTS AND CHEMICALS, INC. (US) 1997-06-18 EP disclosed