Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | GALR3 | O60755 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2949529 | 0.98 | GNAI3 (0.37) | ALDH1A1CYP1A2CYP2D6CYP2C19GNAI3 | |
| SCHEMBL107098 | 0.98 | GNAI3 (0.37) | ALDH1A1CYP1A2CYP2D6CYP2C19GNAI3 | |
| Bromide SCHEMBL2905446 | 0.98 | ALDH1A1 (0.34) | ALDH1A1CYP1A2CYP2D6CYP2C19GNAI3 | |
| SCHEMBL9814327 | 0.98 | GNAI3 (0.37) | ALDH1A1CYP1A2CYP2D6CYP2C19GNAI3 | |
| SCHEMBL21049558 | 0.98 | GNAI3 (0.37) | ALDH1A1CYP1A2CYP2D6CYP2C19GNAI3 | |
| SCHEMBL11652283 | 0.98 | GNAI3 (0.37) | ALDH1A1CYP1A2CYP2D6CYP2C19GNAI3 | |
| SCHEMBL11250645 | 0.98 | GNAI3 (0.37) | ALDH1A1CYP1A2CYP2D6CYP2C19GNAI3 | |
| SCHEMBL1138502 | 0.98 | GNAI3 (0.37) | ALDH1A1CYP1A2CYP2D6CYP2C19GNAI3 | |
| SCHEMBL750715 | 0.98 | GNAI3 (0.37) | ALDH1A1CYP1A2CYP2D6CYP2C19GNAI3 | |
| SCHEMBL108012 | 0.98 | GNAI3 (0.37) | ALDH1A1CYP1A2CYP2D6CYP2C19GNAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0631601-B1 | STABLE, ONE-COMPONENT, CURABLE EPOXY/POLYAMIDE RESIN DISPERSIONS | UNION CAMP CORP (US) | 1997-08-20 | — | — | EP | disclosed |
| US-5605944-A | POLYAMIDE-EPOXY, THERMOPLASTIC-THERMOSET CURABLE RESIN SYSTEMS | UNION CAMP CORPORATION (US) | 1997-02-25 | — | — | US | disclosed |
| WO-1996034040-A1 | HEAT RESISTANT ADHESIVE USED IN STERILIZABLE PACKAGING | UNION CAMP CORPORATION (US) | 1996-10-31 | — | — | WO | disclosed |
| US-5539025-A | MIXTURE FORMED BY BLENDING RESINS WITH DIPOLE CHEMICALS | UNION CAMP CORPORATION (US) | 1996-07-23 | — | — | US | disclosed |
| US-5428083-A | Non-solvated aqueous polyepoxide, non-solvated aqueous polyamide in water soluble, dipolar chemical moiety, and anionic, cationic, or nonionic surfactant | UNION CAMP CORPORATION (US) | 1995-06-27 | — | — | US | disclosed |
| EP-0631601-A1 | STABLE, ONE-COMPONENT, CURABLE EPOXY/POLYAMIDE RESIN DISPERSIONS. | UNION CAMP CORP (US) | 1995-01-04 | — | — | EP | disclosed |
| EP-0631601-A4 | STABLE, ONE-COMPONENT, CURABLE EPOXY/POLYAMIDE RESIN DISPERSIONS. | UNION CAMP CORP (US) | 1994-02-23 | — | — | EP | disclosed |
| WO-1992019677-A1 | STABLE, ONE-COMPONENT, CURABLE EPOXY/POLYAMIDE RESIN DISPERSIONS | UNION CAMP CORPORATION (US) | 1992-11-12 | — | — | WO | disclosed |
| US-5109054-A | Mixing with water and surfactant | UNION CAMP CORPORATION (US) | 1992-04-28 | — | — | US | disclosed |
| US-5025043-A | Low acid and amine number, stability | UNION CAMP CORPORATION (US) | 1991-06-18 | — | — | US | disclosed |
| EP-0327354-A2 | Polymerized fatty acid polyamide resin dispersions and method for the manufacture thereof | Union Camp Corporation (US) | 1989-08-09 | — | — | EP | disclosed |
| EP-0275153-A2 | A process for treating protein fibers to impart antistatic surface modifications | Bristol-Myers Company (US) | 1988-07-20 | — | — | EP | disclosed |