Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPI | P09923 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | XIAP | P98170 | 1/20 | 0.54 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.54 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.44 |
| ▸ | CPA3 | P15088 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.43 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.43 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8835936 | 0.88 | SLC7A5 (0.68) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL288607 | 0.88 | SLC7A5 (0.68) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL28820471 | 0.88 | SLC7A5 (0.68) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL9003809 | 0.87 | ALPI (0.58) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL29160724 | 0.87 | SLC7A5 (0.66) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL9521810 | 0.86 | SLC7A5 (0.54) | SLC7A5HDAC8 | |
| SCHEMBL28126901 | 0.84 | SLC15A1 (0.59) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL3732241 | 0.84 | SLC15A1 (0.59) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL6259105 | 0.83 | ALPI (0.53) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL1537320 | 0.83 | ALPI (0.53) | ALPIPKMPTGS1XIAPSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646316-A | ANTIMETASTASIS AND ANTITUMOR AGENTS | OSTEOARTHRITIS SCIENCES, INC. (US) | 1997-07-08 | — | — | US | disclosed |