Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPI | P09923 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | XIAP | P98170 | 1/20 | 0.58 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.58 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.50 |
| ▸ | CPA3 | P15088 | 1/20 | 0.50 |
| ▸ | ANPEP | P15144 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL288607 | 0.91 | SLC7A5 (0.68) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL8835936 | 0.91 | SLC7A5 (0.68) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL28820471 | 0.91 | SLC7A5 (0.68) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL29160724 | 0.90 | SLC7A5 (0.66) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL8848946 | 0.87 | ALPI (0.54) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL5707698 | 0.85 | SLC7A5 (0.57) | SLC7A5ANPEPHDAC8 | |
| SCHEMBL27566888 | 0.85 | MMP2 (0.47) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL21495214 | 0.85 | SLC7A5 (0.59) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL2494942 | 0.85 | SLC7A5 (0.59) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL1526409 | 0.84 | ALPI (0.63) | ALPIPKMPTGS1XIAPSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404241-B2 | Anti-rhesus D monoclonal antibody | LABORATOIRE FRANCAIS DU FRACTIONNEMENT ET DES BIOTECHNOLOGIES (FR) | 2013-03-26 | — | — | US | disclosed |
| US-20110311556-A1 | ANTI-RHESUS D MONOCLONAL ANTIBODY | LFB-BIOTECHNOLOGIES (FR) | 2011-12-22 | — | — | US | disclosed |
| US-5538876-A | HYDROLYSIS OF ESTERS USING ENZYMES | GIST-BROCADES, N.V. (NL) | 1996-07-23 | — | — | US | disclosed |
| US-4870160-A | PROMOTERS OF HEPARIN BINDING AND CELL ADHESION | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1989-09-26 | — | — | US | disclosed |