SCHEMBL8848968

SCHEMBL8848968

COc1cccc(/N=N/N)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR3E A5X5Y0 1/20 0.59
HTR3B O95264 1/20 0.59
HTR3A P46098 1/20 0.59
HTR3D Q70Z44 1/20 0.59
HTR3C Q8WXA8 1/20 0.59
TAAR1 Q96RJ0 1/20 0.58
MEN1 O00255 3/20 0.53
KMT2A Q03164 3/20 0.53
MAPT P10636 3/20 0.53
LMNA P02545 1/20 0.53
GAA P10253 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
CYP3A4 P08684 2/20 0.50
ALDH1A1 P00352 2/20 0.50
SIGMAR1 Q99720 1/20 0.50
NOS3 P29474 2/20 0.49
NOS1 P29475 2/20 0.49
NOS2 P35228 2/20 0.49
RAB9A P51151 2/20 0.48
NPC1 O15118 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17707284 0.87 HTR3E (0.62) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL10818541 0.87 HTR3E (0.62) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL7047246 0.83 HTR3E (0.63) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL1405164 0.82 GSK3B (0.57) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL14006059 0.82 HTR3E (0.56) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL1405162 0.82 GSK3B (0.57) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL1971602 0.79 HTR3E (0.62) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL2874120 0.78 NOS1 (0.44) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL2874123 0.78 NOS1 (0.44) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL18643913 0.77 MEN1 (0.56) HTR3EHTR3BHTR3AHTR3DHTR3C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0808884-A2 Heat curable two-component lacquer Feinchemie GmbH Sebnitz (DE) 1997-11-26 EP disclosed