SCHEMBL8849042

SCHEMBL8849042

CCOC(OCC)[SiH](CC)CC

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.47
THRB P10828 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8849111 0.77 THRB (0.38) LMNATHRB
SCHEMBL8511715 0.75 LMNA (0.47) LMNATHRB
Ammonia Solution, Strong SCHEMBL17800302 0.75 MEN1 (0.34) LMNA
SCHEMBL8849869 0.75 LMNA (0.41) LMNATHRB
SCHEMBL18787584 0.73 THRB (0.47) LMNATHRB
SCHEMBL7114108 0.73 LMNA (0.53) LMNATHRB
SCHEMBL8849027 0.73 THRB (0.35) LMNATHRB
SCHEMBL8849265 0.71 THRB (0.44) LMNATHRB
SCHEMBL8848879 0.71
SCHEMBL4811837 0.71 LMNA (0.43) LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0671417-B1 Components and catalysts for the copolymerisation of olefins MONTELL NORTH AMERICA INC (US) 1997-05-02 EP disclosed
EP-0437263-B1 Components and catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC (US) 1995-11-08 EP disclosed
EP-0671417-A2 Components and catalysts for the copolymerisation of olefins MONTELL NORTH AMERICA INC. (US) 1995-09-13 EP disclosed
US-5106807-A Coordination catalysts comprising a dihydrocarbylethermethyl silane, a titanium halide and a magnesium halide support; stereospecific HIMONT INCORPORATED (US) 1992-04-21 US disclosed
EP-0437263-A1 Components and catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC. (US) 1991-07-17 EP disclosed