SCHEMBL8849540

SCHEMBL8849540

Cc1ccc(N(c2ccc(C#N)cc2)c2ccc(C#N)cc2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.73
CYP2A6 P11509 2/20 0.73
HCRTR2 O43614 1/20 0.46
TSHR P16473 2/20 0.42
ENPP2 Q13822 1/20 0.41
RORC P51449 4/20 0.41
BCHE P06276 1/20 0.41
ACHE P22303 1/20 0.41
CA12 O43570 1/20 0.41
CA2 P00918 1/20 0.41
CA3 P07451 1/20 0.41
CA6 P23280 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
AR P10275 1/20 0.40
LOXL2 Q9Y4K0 1/20 0.39
KDM4E B2RXH2 1/20 0.38
LMNA P02545 1/20 0.38
GAA P10253 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12048268 0.92 ALDH1A1 (0.61) ALDH1A1CYP2A6HCRTR2TSHRENPP2
SCHEMBL15223149 0.89 ALDH1A1 (0.57) ALDH1A1CYP2A6HCRTR2RORCKDM4E
SCHEMBL995812 0.88 CA2 (0.50) ALDH1A1CYP2A6TSHRENPP2CA12
SCHEMBL15906453 0.87 ALDH1A1 (0.55) ALDH1A1CYP2A6HCRTR2TSHRENPP2
SCHEMBL18390810 0.87 ALDH1A1 (0.55) ALDH1A1CYP2A6HCRTR2ACHEAR
SCHEMBL12048231 0.86 ALDH1A1 (0.53) ALDH1A1CYP2A6HCRTR2TSHRRORC
SCHEMBL19888145 0.86 CYP2A6 (0.53) ALDH1A1CYP2A6HCRTR2TSHRRORC
SCHEMBL46818 0.85
P-Xylene SCHEMBL3926102 0.85 CYP2A6 (1.00) ALDH1A1CYP2A6TSHRENPP2BCHE
SCHEMBL27329500 0.85 CYP2A6 (1.00) ALDH1A1CYP2A6TSHRENPP2BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3882243-B1 DICYANOPYRAZINE COMPOUND, LUMINESCENT MATERIAL AND LIGHT TRANSMITTER USING SAME UNIV KYUSHU NAT UNIV CORP (JP) 2023-01-04 EP disclosed
US-5633337-A Aromatic benzobisazole polymers and copolymers incorporating diphenylamino moieties THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1997-05-27 US disclosed
US-5536866-A Triarylamine-based dinitrile and dicarboxylic acid monomers THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1996-07-16 US disclosed