Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | PPARD | Q03181 | 4/20 | 0.49 |
| ▸ | PPARA | Q07869 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | FABP4 | P15090 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8849571 | 1.00 | LTB4R (0.53) | LTB4RNFKB1NFKB2RELAOXER1 | |
| SCHEMBL8849821 | 0.90 | LTB4R (0.64) | LTB4RNFKB1NFKB2RELAPPARG | |
| SCHEMBL8849902 | 0.90 | LTB4R (0.64) | LTB4RNFKB1NFKB2RELAPPARG | |
| SCHEMBL8870066 | 0.90 | LTB4R (0.64) | LTB4RNFKB1NFKB2RELAPPARG | |
| SCHEMBL8849832 | 0.90 | LTB4R (0.64) | LTB4RNFKB1NFKB2RELAPPARG | |
| SCHEMBL8849878 | 0.90 | LTB4R (0.64) | LTB4RNFKB1NFKB2RELAPPARG | |
| SCHEMBL8849921 | 0.90 | LTB4R (0.64) | LTB4RNFKB1NFKB2RELAPPARG | |
| SCHEMBL8850289 | 0.90 | LTB4R (0.64) | LTB4RNFKB1NFKB2RELAPPARG | |
| SCHEMBL8850327 | 0.88 | PPARG (0.57) | LTB4ROXER1PPARGPPARA | |
| SCHEMBL8849881 | 0.88 | PPARG (0.57) | LTB4ROXER1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599975-A | ANTICOAGULANTS | ADIR ET COMPAGNIE (FR) | 1997-02-04 | — | — | US | claimed |
| EP-0650953-B1 | Cyclised analogs of metabolites of fatty acids, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1997-06-04 | — | — | EP | disclosed |
| US-5599975-A | ANTICOAGULANTS | ADIR ET COMPAGNIE (FR) | 1997-02-04 | — | — | US | disclosed |
| EP-0650953-A1 | Cyclised analogs of metabolites of fatty acids, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1995-05-03 | — | — | EP | disclosed |