Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 3/20 | 0.64 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.47 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | FABP4 | P15090 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8849878 | 1.00 | LTB4R (0.64) | LTB4RLTB4R2PTGER2PTGER3PTGER4 | |
| SCHEMBL8849821 | 1.00 | LTB4R (0.64) | LTB4RLTB4R2PTGER2PTGER3PTGER4 | |
| SCHEMBL8849902 | 1.00 | LTB4R (0.64) | LTB4RLTB4R2PTGER2PTGER3PTGER4 | |
| SCHEMBL8849921 | 1.00 | LTB4R (0.64) | LTB4RLTB4R2PTGER2PTGER3PTGER4 | |
| SCHEMBL8850289 | 1.00 | LTB4R (0.64) | LTB4RLTB4R2PTGER2PTGER3PTGER4 | |
| SCHEMBL8849832 | 1.00 | LTB4R (0.64) | LTB4RLTB4R2PTGER2PTGER3PTGER4 | |
| SCHEMBL8849564 | 0.90 | LTB4R (0.53) | LTB4RPPARGKDM4EMEN1USP2 | |
| SCHEMBL8849571 | 0.90 | LTB4R (0.53) | LTB4RPPARGKDM4EMEN1USP2 | |
| SCHEMBL8869033 | 0.88 | LTB4R (0.51) | LTB4RPPARGPPARANFKB1 | |
| SCHEMBL8869038 | 0.88 | LTB4R (0.51) | LTB4RPPARGPPARANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599975-A | ANTICOAGULANTS | ADIR ET COMPAGNIE (FR) | 1997-02-04 | — | — | US | disclosed |