Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8011207 | 0.89 | TSHR (0.58) | TSHRTP53ADRA2AADRA2BADRA2C | |
| SCHEMBL28823390 | 0.83 | TP53 (0.55) | TSHRTP53HTR1DATMCYP1A2 | |
| SCHEMBL28037910 | 0.83 | TP53 (0.55) | TSHRTP53HTR1DATMCYP1A2 | |
| SCHEMBL9241092 | 0.80 | ATM (0.50) | TSHRTP53ADRA2AADRA2BADRA2C | |
| SCHEMBL23248048 | 0.80 | TP53 (0.47) | TSHRTP53ELANE | |
| SCHEMBL29671366 | 0.80 | TP53 (0.47) | TSHRTP53ELANE | |
| SCHEMBL4428392 | 0.79 | TP53 (0.51) | TSHRTP53ATMCYP1A2CYP2C19 | |
| SCHEMBL16245780 | 0.78 | LMNA (0.40) | TSHRTP53ELANEALDH1A1HTT | |
| SCHEMBL13802284 | 0.78 | ESR2 (0.49) | TSHRTP53ELANENR3C1PGR | |
| SCHEMBL16245769 | 0.77 | TSHR (0.44) | TSHRTP53NFKB1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3218459-B1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2025-09-03 | — | — | EP | claimed |
| CN-107074712-B | Improvements in or relating to organic compounds | 奇华顿股份有限公司 | 2021-06-29 | — | — | CN | claimed |
| EP-2994448-B1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2019-07-31 | — | — | EP | claimed |
| US-20180282662-A1 | Process | GIVAUDAN S.A. (CH) | 2018-10-04 | — | — | US | claimed |
| US-9988592-B2 | Organic compounds | Givaudan, S.A. (CH) | 2018-06-05 | — | — | US | claimed |
| EP-3218459-A1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | Givaudan S.A. (CH) | 2017-09-20 | — | — | EP | claimed |
| US-20170218299-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2017-08-03 | — | — | US | claimed |
| US-9656938-B2 | Organic compounds | GIVAUDAN S.A. (CH) | 2017-05-23 | — | — | US | claimed |
| WO-2016074697-A1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2016-05-19 | — | — | WO | claimed |
| US-20160075627-A1 | ORGANIC COMPOUNDS | GIVAUDAN S.A. (CH) | 2016-03-17 | — | — | US | claimed |
| EP-2994448-A1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | Givaudan SA (CH) | 2016-03-16 | — | — | EP | claimed |
| WO-2014180952-A1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2014-11-13 | — | — | WO | claimed |
| US-10457891-B2 | Organic compounds | GIVAUDAN S.A. (CH) | 2019-10-29 | — | — | US | disclosed |
| EP-2994448-B1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2019-07-31 | — | — | EP | disclosed |
| US-20180251706-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2018-09-06 | — | — | US | disclosed |
| US-9988592-B2 | Organic compounds | Givaudan, S.A. (CH) | 2018-06-05 | — | — | US | disclosed |
| EP-0652861-B1 | NOVEL AROMATIC COMPOUNDS AND THEIR USE IN PERFUME PRODUCTS | FIRMENICH & CIE (CH) | 1997-09-03 | — | — | EP | disclosed |
| US-5527769-A | AROMATIC ALDEHYDES OR ACETALS IMPART FLORAL FRAGRANCES | FIRMENICH SA (CH) | 1996-06-18 | — | — | US | disclosed |
| EP-0652861-A1 | NOVEL AROMATIC COMPOUNDS AND THEIR USE IN PERFUME PRODUCTS. | FIRMENICH & CIE (CH) | 1995-05-17 | — | — | EP | disclosed |
| WO-1994027946-A1 | NOVEL AROMATIC COMPOUNDS AND THEIR USE IN PERFUME PRODUCTS | FIRMENICH S.A. (CH) | 1994-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160075627-A1 | ORGANIC COMPOUNDS | AOX1, TYR, ALK | TSHR 3983/4885TP53 923/4885ADRA2A 1709/4885 |
| US-20180282662-A1 | Process | CUL4B, RNF10, BICRA | TSHR 3485/4885TP53 701/4885ADRA2A 1278/4885 |
| US-20180251706-A1 | ORGANIC COMPOUNDS | AOX1, TYR, ALK | TSHR 3983/4885TP53 923/4885ADRA2A 1709/4885 |
| US-20170218299-A1 | ORGANIC COMPOUNDS | AOX1, TYR, ALK | TSHR 3983/4885TP53 923/4885ADRA2A 1709/4885 |
| US-10457891-B2 | Organic compounds | AOX1, TYR, ALK | TSHR 3983/4885TP53 923/4885ADRA2A 1709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.