Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.57 |
| ▸ | PPARA | Q07869 | 4/20 | 0.56 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8850327 | 1.00 | PPARG (0.57) | PPARGPPARAPTGER2PTGER4PTGER3 | |
| SCHEMBL8849881 | 1.00 | PPARG (0.57) | PPARGPPARAPTGER2PTGER4PTGER3 | |
| SCHEMBL8870668 | 0.90 | LTB4R (0.50) | PPARGPPARAPTGER2PTGER4PTGER3 | |
| SCHEMBL8870701 | 0.90 | LTB4R (0.50) | PPARGPPARAPTGER2PTGER4PTGER3 | |
| SCHEMBL8849564 | 0.88 | LTB4R (0.53) | PPARGPPARAOXER1LTB4R | |
| SCHEMBL8849571 | 0.88 | LTB4R (0.53) | PPARGPPARAOXER1LTB4R | |
| SCHEMBL9239542 | 0.86 | PPARG (0.53) | PPARGPPARAPTGER4PTGER3ALOX5 | |
| SCHEMBL8849505 | 0.84 | PPARG (0.52) | PPARGPPARAPTGER2PTGER4PTGER3 | |
| SCHEMBL8849580 | 0.84 | PPARG (0.52) | PPARGPPARAPTGER2PTGER4PTGER3 | |
| SCHEMBL8849520 | 0.84 | PPARG (0.52) | PPARGPPARAPTGER2PTGER4PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650953-B1 | Cyclised analogs of metabolites of fatty acids, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1997-06-04 | — | — | EP | disclosed |
| US-5599975-A | ANTICOAGULANTS | ADIR ET COMPAGNIE (FR) | 1997-02-04 | — | — | US | disclosed |
| EP-0650953-A1 | Cyclised analogs of metabolites of fatty acids, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1995-05-03 | — | — | EP | disclosed |