Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | DUT | P33316 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8850489 | 0.93 | SMN1; SMN2 (0.49) | HTTSMN1; SMN2MEN1ALDH1A1HPGD | |
| SCHEMBL27515247 | 0.89 | SMN1; SMN2 (0.48) | HTTSMN1; SMN2MEN1ALDH1A1HPGD | |
| SCHEMBL6196490 | 0.86 | SMN1; SMN2 (0.49) | HTTSMN1; SMN2MEN1ALDH1A1HPGD | |
| SCHEMBL6194946 | 0.86 | HTT (0.49) | HTTSMN1; SMN2MEN1ALDH1A1HPGD | |
| SCHEMBL8850068 | 0.85 | HTT (0.45) | HTTSMN1; SMN2MEN1ALDH1A1HPGD | |
| SCHEMBL6195834 | 0.84 | HTT (0.47) | HTTSMN1; SMN2MEN1ALDH1A1HPGD | |
| SCHEMBL6197397 | 0.83 | HTT (0.46) | HTTSMN1; SMN2MEN1ALDH1A1HPGD | |
| SCHEMBL27480829 | 0.83 | HTT (0.50) | HTTSMN1; SMN2MEN1ALDH1A1HPGD | |
| SCHEMBL6196888 | 0.83 | HTT (0.48) | HTTSMN1; SMN2MEN1ALDH1A1HPGD | |
| SCHEMBL8850637 | 0.82 | SMN1; SMN2 (0.49) | HTTSMN1; SMN2MEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688815-A | COMPOUNDS FOR REMOVAL OF EXCESS IRON IN MAMMALS | CIBA GEIGY CORPORATION (US) | 1997-11-18 | — | — | US | disclosed |
| CN-1151399-A | Novel hydroxylpyridinones | CIBA GEIGY AG (CH) | 1997-06-11 | — | — | CN | disclosed |