Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27515247 | 0.96 | SMN1; SMN2 (0.48) | SMN1; SMN2HTTMEN1ALDH1A1HPGD | |
| SCHEMBL8849907 | 0.93 | HTT (0.46) | SMN1; SMN2HTTMEN1ALDH1A1HPGD | |
| SCHEMBL8850637 | 0.89 | SMN1; SMN2 (0.49) | SMN1; SMN2HTTMEN1ALDH1A1HPGD | |
| SCHEMBL6199982 | 0.88 | SMN1; SMN2 (0.53) | SMN1; SMN2HTTMEN1ALDH1A1HPGD | |
| SCHEMBL6196536 | 0.88 | SMN1; SMN2 (0.53) | SMN1; SMN2HTTMEN1ALDH1A1HPGD | |
| SCHEMBL6196490 | 0.80 | SMN1; SMN2 (0.49) | SMN1; SMN2HTTMEN1ALDH1A1HPGD | |
| SCHEMBL6194946 | 0.80 | HTT (0.49) | SMN1; SMN2HTTMEN1ALDH1A1HPGD | |
| SCHEMBL8850313 | 0.80 | TBXA2R (0.40) | ALDH1A1KMT2ANPSR1PTGDR2 | |
| SCHEMBL8850113 | 0.79 | SMN1; SMN2 (0.40) | SMN1; SMN2HTTMEN1ALDH1A1HPGD | |
| SCHEMBL8850068 | 0.79 | HTT (0.45) | SMN1; SMN2HTTMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688815-A | COMPOUNDS FOR REMOVAL OF EXCESS IRON IN MAMMALS | CIBA GEIGY CORPORATION (US) | 1997-11-18 | — | — | US | disclosed |
| CN-1151399-A | Novel hydroxylpyridinones | CIBA GEIGY AG (CH) | 1997-06-11 | — | — | CN | disclosed |