Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31429834 | 0.80 | MTNR1A (0.61) | PTGS1AKR1C3AKR1C2TDP1MTNR1A | |
| SCHEMBL7925457 | 0.80 | MTNR1A (0.61) | PTGS1AKR1C3AKR1C2TDP1MTNR1A | |
| SCHEMBL30692247 | 0.77 | MTNR1A (0.64) | TDP1MTNR1AMTNR1BNQO2 | |
| SCHEMBL3914252 | 0.77 | MTNR1A (0.64) | TDP1MTNR1AMTNR1BNQO2 | |
| SCHEMBL1041432 | 0.77 | CYP1A2 (0.55) | HDAC8MTNR1AMTNR1B | |
| SCHEMBL453836 | 0.76 | AKR1C2 (0.59) | PTGS1AKR1C3AKR1C2MTNR1AMTNR1B | |
| SCHEMBL11466749 | 0.76 | PTGS1 (0.59) | PTGS1AKR1C3AKR1C2MTNR1AMTNR1B | |
| SCHEMBL4749622 | 0.76 | MTNR1A (0.63) | TDP1MTNR1AMTNR1BNQO2 | |
| SCHEMBL13612562 | 0.76 | PTGS1 (0.52) | PTGS1AKR1C3AKR1C2MTNR1AL3MBTL1 | |
| SCHEMBL28003639 | 0.75 | TDP1 (0.67) | TDP1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780358-A1 | A process for the resolution of 6-methoxy-alpha-methyl-2-naphthaleneacetic racemic acid into its enantiomers | FARCHEMIA S.r.l. (IT) | 1997-06-25 | — | — | EP | claimed |