Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL8942306 | 0.98 | PTGS2 (0.31) | PTGS2PTGS1CA1CA2CA9 | |
| Sulfuric Acid SCHEMBL8849965 | 0.93 | CYP2C19 (0.31) | PTGS2PTGS1CYP2C19 | |
| Sulfuric Acid SCHEMBL8850659 | 0.91 | SOS1 (0.32) | PTGS2PTGS1CA1CA2CA9 | |
| Sulfuric Acid SCHEMBL8942106 | 0.89 | SOS1 (0.31) | PTGS2PTGS1 | |
| Hydrochloric Acid SCHEMBL8850304 | 0.86 | — | — | |
| Sulfuric Acid SCHEMBL8849819 | 0.84 | GPR27 (0.32) | CA2 | |
| Hydrochloric Acid SCHEMBL8849872 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL8942441 | 0.84 | — | — | |
| Sulfuric Acid SCHEMBL11247449 | 0.82 | — | — | |
| SCHEMBL8849814 | 0.82 | POLB (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0606058-B1 | Halogenated cinnamic acids and their esters as well as processes for their preparation and halogenated aryldiazonium salts | HOECHST AG (DE) | 1997-11-05 | — | — | EP | disclosed |
| US-5516932-A | Halogenated cinnamic acids and esters thereof, processes for the preparation thereof and halogenated aryldiazonium salts | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-05-14 | — | — | US | disclosed |
| EP-0606058-A2 | Halogenated cinnamic acids and their esters as well as processes for their preparation and halogenated aryldiazonium salts | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-07-13 | — | — | EP | disclosed |