Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2245821 | 0.92 | TSHR (0.48) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| SCHEMBL8851060 | 0.92 | TSHR (0.48) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| SCHEMBL268165 | 0.89 | TSHR (0.51) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| SCHEMBL28412602 | 0.88 | THRB (0.53) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| SCHEMBL8850718 | 0.88 | THRB (0.48) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| SCHEMBL28149678 | 0.88 | THRB (0.48) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| SCHEMBL23636 | 0.88 | THRB (0.48) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| SCHEMBL64442 | 0.87 | TSHR (0.44) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| SCHEMBL19342611 | 0.87 | THRB (0.50) | TSHRTHRBALDH1A1 | |
| SCHEMBL10391726 | 0.86 | THRB (0.47) | TSHRTHRBALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661307-B1 | Transparent resin and plastic lens | HITACHI CHEMICAL CO LTD (JP) | 1997-10-15 | — | — | EP | disclosed |
| US-5663264-A | OF A COPOLYMER CONTAINING AN ALKYLENE OXIDE MONOMER, A POLYFUNCTIONAL (METH)ACRYLATE MONOMER AND A VINYL MONOMER | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1997-09-02 | — | — | US | disclosed |
| US-5583191-A | FORMED OF TRANSPARENT RESIN OBTAINED BY POLYMERIZING MONOMER HAVING ALKYLENE OXIDE GROUP, POLYFUNCTIONAL (METH)ACRYLATE HAVING DIVALENT BRANCED HYDROCARBON GROUP, OPTIONAL ADDITIONAL VINYL MONOMER; HEAT RESISTANCE | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1996-12-10 | — | — | US | disclosed |