Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL7773090 | 1.00 | TSHR (0.59) | TSHRTDP1PDE4AOR51E2TP53 | |
| Propylene Glycol SCHEMBL17841687 | 0.85 | TDP1 (0.62) | TSHRTDP1PDE4AOR51E2TP53 | |
| Propylene Glycol SCHEMBL5603965 | 0.85 | TDP1 (0.62) | TSHRTDP1PDE4AOR51E2TP53 | |
| Lactic Acid SCHEMBL692985 | 0.85 | TP53 (0.69) | TSHRTDP1PDE4AOR51E2TP53 | |
| Lactic Acid SCHEMBL8850838 | 0.85 | TP53 (0.69) | TSHRTDP1PDE4AOR51E2TP53 | |
| Propylene Glycol SCHEMBL3270603 | 0.85 | TDP1 (0.62) | TSHRTDP1PDE4AOR51E2TP53 | |
| Propylene Glycol SCHEMBL4337036 | 0.84 | TDP1 (0.71) | TSHRTDP1PDE4AOR51E2TP53 | |
| Propylene Glycol SCHEMBL320017 | 0.84 | — | — | |
| Propylene Glycol SCHEMBL29352119 | 0.84 | — | — | |
| Propylene Glycol SCHEMBL28574118 | 0.84 | TDP1 (0.71) | TSHRTDP1PDE4AOR51E2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0785714-A1 | ANTIMICROBIAL COMPOSITION | MOBERG, Sven (SE) | 1997-07-30 | — | — | EP | disclosed |
| WO-1996011572-A1 | ANTIMICROBIAL COMPOSITION | MOBERG SVEN (SE) | 1996-04-25 | — | — | WO | disclosed |