Propene

Propene

SCHEMBL8850806

C=C(C)C(=O)OCCOC(=O)C(=C)C.C=CC.C=CC.C=CC.C=CC.C=CC.C=CC.C=CC.C=CC.C=CC.C=CC.C=CC.C=CC.C=CC

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.63
TSHR P16473 9/20 0.55
ALDH1A1 P00352 7/20 0.44
TDP1 Q9NUW8 2/20 0.41
POLB P06746 1/20 0.41
APEX1 P27695 1/20 0.41
HTT P42858 1/20 0.41
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
TP53 P04637 2/20 0.38
HIF1A Q16665 2/20 0.38
HSD17B10 Q99714 1/20 0.38
HPGD P15428 1/20 0.34
CYP3A4 P08684 1/20 0.33
CHRM5 P08912 1/20 0.32
CHRM1 P11229 1/20 0.32
CHRM3 P20309 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propene SCHEMBL41274 1.00 THRB (0.63) THRBTSHRALDH1A1TDP1POLB
Propene SCHEMBL6823541 1.00 THRB (0.63) THRBTSHRALDH1A1TDP1POLB
Propene SCHEMBL2404837 1.00 THRB (0.63) THRBTSHRALDH1A1TDP1POLB
Propene SCHEMBL8851515 1.00 THRB (0.63) THRBTSHRALDH1A1TDP1POLB
Propene SCHEMBL3343927 1.00 THRB (0.63) THRBTSHRALDH1A1TDP1POLB
Propene SCHEMBL11112032 1.00 THRB (0.63) THRBTSHRALDH1A1TDP1POLB
Propene SCHEMBL156576 1.00 THRB (0.63) THRBTSHRALDH1A1TDP1POLB
Propene SCHEMBL672400 1.00 THRB (0.63) THRBTSHRALDH1A1TDP1POLB
Propene SCHEMBL7154370 1.00 THRB (0.63) THRBTSHRALDH1A1TDP1POLB
Propene SCHEMBL6548298 1.00 THRB (0.63) THRBTSHRALDH1A1TDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661307-B1 Transparent resin and plastic lens HITACHI CHEMICAL CO LTD (JP) 1997-10-15 EP disclosed
US-5663264-A OF A COPOLYMER CONTAINING AN ALKYLENE OXIDE MONOMER, A POLYFUNCTIONAL (METH)ACRYLATE MONOMER AND A VINYL MONOMER HITACHI CHEMICAL COMPANY, LTD. (JP) 1997-09-02 US disclosed
US-5583191-A FORMED OF TRANSPARENT RESIN OBTAINED BY POLYMERIZING MONOMER HAVING ALKYLENE OXIDE GROUP, POLYFUNCTIONAL (METH)ACRYLATE HAVING DIVALENT BRANCED HYDROCARBON GROUP, OPTIONAL ADDITIONAL VINYL MONOMER; HEAT RESISTANCE HITACHI CHEMICAL COMPANY, LTD. (JP) 1996-12-10 US disclosed
EP-0661307-A2 Transparent resin and plastic lens HITACHI CHEMICAL CO., LTD. (JP) 1995-07-05 EP disclosed