Propene

Propene

SCHEMBL2404837

C=C(C)C(=O)OCCOC(=O)C(=C)C.C=CC.C=CC.C=CC.C=CC.C=CC.C=CC.C=CC.C=CC.C=CC

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.63
TSHR P16473 9/20 0.55
ALDH1A1 P00352 7/20 0.44
TDP1 Q9NUW8 2/20 0.41
POLB P06746 1/20 0.41
APEX1 P27695 1/20 0.41
HTT P42858 1/20 0.41
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
TP53 P04637 2/20 0.38
HIF1A Q16665 2/20 0.38
HSD17B10 Q99714 1/20 0.38
HPGD P15428 1/20 0.34
CYP3A4 P08684 1/20 0.33
CHRM5 P08912 1/20 0.32
CHRM1 P11229 1/20 0.32
CHRM3 P20309 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propene SCHEMBL41274 1.00 THRB (0.63) THRBTSHRALDH1A1TDP1POLB
Propene SCHEMBL6823541 1.00 THRB (0.63) THRBTSHRALDH1A1TDP1POLB
Propene SCHEMBL8851515 1.00 THRB (0.63) THRBTSHRALDH1A1TDP1POLB
Propene SCHEMBL3343927 1.00 THRB (0.63) THRBTSHRALDH1A1TDP1POLB
Propene SCHEMBL11112032 1.00 THRB (0.63) THRBTSHRALDH1A1TDP1POLB
Propene SCHEMBL8850806 1.00 THRB (0.63) THRBTSHRALDH1A1TDP1POLB
Propene SCHEMBL156576 1.00 THRB (0.63) THRBTSHRALDH1A1TDP1POLB
Propene SCHEMBL672400 1.00 THRB (0.63) THRBTSHRALDH1A1TDP1POLB
Propene SCHEMBL7154370 1.00 THRB (0.63) THRBTSHRALDH1A1TDP1POLB
Propene SCHEMBL6548298 1.00 THRB (0.63) THRBTSHRALDH1A1TDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240197577-A1 SELF-ADHESIVE DENTAL MATERIAL KULZER GMBH (DE) 2024-06-20 US claimed
EP-4312945-A1 SELF-ADHESIVE DENTAL MATERIAL Kulzer GmbH (DE) 2024-02-07 EP claimed
WO-2022207877-A1 SELF-ADHESIVE DENTAL MATERIAL KULZER GMBH (DE) 2022-10-06 WO claimed
US-8529789-B2 Curable composition TOKUYAMA CORPORATION (JP) 2013-09-10 US claimed
US-8012596-B2 Photochromic lens substrate TOKUYAMA CORPORATION (JP) 2011-09-06 US claimed
EP-1607418-B1 POLYMERIZATION CURABLE COMPOSITION TOKUYAMA CORP (JP) 2008-07-09 EP claimed
US-20240423878-A2 SELF-ADHESIVE FISSURE SEALANT KULZER GMBH (DE) 2024-12-26 US disclosed
US-20240216229-A1 SELF-ADHESIVE FISSURE SEALANT KULZER GMBH (DE) 2024-07-04 US disclosed
US-20240197577-A1 SELF-ADHESIVE DENTAL MATERIAL KULZER GMBH (DE) 2024-06-20 US disclosed
EP-4312947-A1 SELF-ADHESIVE FISSURE SEALANT Kulzer GmbH (DE) 2024-02-07 EP disclosed
US-20230375930-A1 PHOTOSENSITIVE RESIN MULTILAYER BODY ASAHI KASEI KABUSHIKI KAISHA (JP) 2023-11-23 US disclosed
WO-2022207879-A1 SELF-ADHESIVE FISSURE SEALANT KULZER GMBH (DE) 2022-10-06 WO disclosed
US-8529789-B2 Curable composition TOKUYAMA CORPORATION (JP) 2013-09-10 US disclosed
EP-0218229-B1 THERMOPLASTIC RESIN COMPOSITION AND PROCESS FOR ITS PREPARATION DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1991-09-25 EP disclosed
EP-0430209-A2 Resin composition for cast polymerization MITSUBISHI RAYON CO., LTD. (JP) 1991-06-05 EP disclosed
US-4812516-A EMULSION POLYMERS, MOLDING MATERIALS, NONCRACKING DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1989-03-14 US disclosed
US-4774291-A EMULSION POLYMER BLENDS OF ACRYLATE POLYMERS AND STYRENE POLYMERS DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1988-09-27 US disclosed
US-4740553-A Molding composition containing an elastomer-containing styrene resin, a polycarbonate resin, and a polymer of an acrylate monomer possessing environmental stress cracking resistance DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1988-04-26 US disclosed
EP-0230030-A2 Polymer composition DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1987-07-29 EP disclosed
EP-0218229-A2 Thermoplastic resin composition and process for its preparation DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1987-04-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240197577-A1 SELF-ADHESIVE DENTAL MATERIAL CAD, MTHFD2, MAT2B THRB 344/4885TSHR 1427/4885ALDH1A1 273/4885
US-20240423878-A2 SELF-ADHESIVE FISSURE SEALANT ESD, GFER, FUS THRB 894/4885TSHR 1186/4885ALDH1A1 318/4885
US-20240216229-A1 SELF-ADHESIVE FISSURE SEALANT ESD, GFER, FUS THRB 894/4885TSHR 1186/4885ALDH1A1 318/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.