SCHEMBL8851985

SCHEMBL8851985

Cc1cc(-c2cc(C)c(C#N)c(C)c2)cc(C)c1C#N

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.46
ALDH1A1 P00352 5/20 0.46
HPGD P15428 3/20 0.46
HSD17B10 Q99714 2/20 0.46
MAPT P10636 1/20 0.46
ALOX15 P16050 1/20 0.46
APOBEC3G Q9HC16 1/20 0.46
HAVCR2 Q8TDQ0 1/20 0.46
RECQL P46063 4/20 0.43
TDP1 Q9NUW8 2/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
UPP1 Q16831 1/20 0.43
LMNA P02545 2/20 0.42
GAA P10253 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
TP53 P04637 1/20 0.41
CYP3A4 P08684 1/20 0.41
TSHR P16473 1/20 0.41
CA1 P00915 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21095364 0.92 KDM4E (0.42) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL16848657 0.86 LMNA (0.46) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL16848658 0.86 LMNA (0.46) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL1344362 0.82 KDM4E (0.46) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL2153883 0.80 KDM4E (0.45) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL29306061 0.78 CYP1A1 (0.50) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL145353 0.78 KDM4E (0.43) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL1128572 0.78 UPP1 (0.50) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL4434407 0.78 KDM4E (0.43) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL10293349 0.78 KDM4E (0.43) KDM4EALDH1A1HPGDHSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0594644-B1 ANISOTROPIC CONDUCTIVE ADHESIVE FILM MINNESOTA MINING & MFG (US) 1997-03-12 EP disclosed