SCHEMBL1344362

SCHEMBL1344362

Cc1cc(C)c(C#N)c(C)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.46
ALDH1A1 P00352 5/20 0.46
MAPT P10636 2/20 0.46
HPGD P15428 2/20 0.46
HSD17B10 Q99714 2/20 0.46
ALOX15 P16050 1/20 0.46
APOBEC3G Q9HC16 1/20 0.46
HAVCR2 Q8TDQ0 1/20 0.46
RECQL P46063 4/20 0.43
KMT2A Q03164 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
MEN1 O00255 1/20 0.43
UPP1 Q16831 1/20 0.43
LMNA P02545 2/20 0.42
XBP1 P17861 1/20 0.40
HTT P42858 1/20 0.40
USP2 O75604 1/20 0.39
RAPGEF4 Q8WZA2 1/20 0.39
RXFP1 Q9HBX9 1/20 0.38
MAPK1 P28482 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2154900 0.88 CYP1A2 (0.50) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL16639871 0.85 KDM4E (0.41) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL11284603 0.83 KDM4E (0.48) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL14473069 0.83 TRPV4 (0.46) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL10914092 0.83 KDM4E (0.39) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL14434049 0.83 KDM4E (0.40) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL8851985 0.82 KDM4E (0.46) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL12681314 0.81 KDM4E (0.38) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL2153883 0.80 KDM4E (0.45) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL18602766 0.79 ACHE (0.46) KDM4EALDH1A1MAPTHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4504803-A1 PALLADIUM CATALYSTS FOR FORMING VINYL ADDITION POLYMERS HAVING IMPROVED FILM FORMING PROPERTIES Promerus, LLC (US) 2025-02-12 EP claimed
CN-119137161-A Palladium catalyst for vinyl addition polymer formation with improved film forming properties 普罗米鲁斯有限责任公司 2024-12-13 CN claimed
WO-2023196366-A1 PALLADIUM CATALYSTS FOR FORMING VINYL ADDITION POLYMERS HAVING IMPROVED FILM FORMING PROPERTIES PROMERUS, LLC (US) 2023-10-12 WO claimed
US-20230312775-A1 PALLADIUM CATALYSTS FOR FORMING VINYL ADDITION POLYMERS HAVING IMPROVED FILM FORMING PROPERTIES PROMERUS, LLC (US) 2023-10-05 US claimed
US-20230193032-A1 BIO-AGENT FOR EXTRACTION OF ASPHALTENE FROM SILICEOUS SURFACES NATIONAL SCIENCE FOUNDATION 2023-06-22 US claimed
US-9415354-B2 Organopalladium compounds as polymerization catalysts PROMERUS, LLC (US) 2016-08-16 US claimed
US-20160046657-A1 ORGANOPALLADIUM COMPOUNDS AS POLYMERIZATION CATALYSTS SUMITOMO BAKELITE CO., LTD. (JP) 2016-02-18 US claimed
EP-4638569-A1 SUPPORTED MEMBRANES BY THERMAL AND UV INITIATED MASS POLYMERIZATION Promerus, LLC (US) 2025-10-29 EP disclosed
EP-4612126-A1 COMPOSITIONS INCLUDING A MIXTURE OF ISOMERS OF ITACONIMIDE NORBORNENE AND CITRACONIMIDE NORBORNENE 3M Innovative Properties Company (US) 2025-09-10 EP disclosed
CN-120152955-A Compositions comprising isomer mixtures of itaconimide norbornene and citraconimide norbornene 3M创新有限公司 2025-06-13 CN disclosed
US-20250177927-A1 SUPPORTED MEMBRANES BY THERMAL AND UV INITITATED MASS POLYMERIZATION PROMERUS, LLC (US) 2025-06-05 US disclosed
US-20250129016-A1 PHOTOREDOX METHODS FOR RADIOCYANATION OF ARENES AND USE THEREOF THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL 2025-04-24 US disclosed
US-12251668-B2 Supported membranes by thermal and UV initiated mass polymerization PROMERUS, LLC (US) 2025-03-18 US disclosed
US-5891894-A 2-AMINO OXAZOLE DERIVATIVES; ANTAGONISTS OF PLATELET ACTIVATING FACTOR USEFUL IN TREATMENT OF ASTHMA, INFLAMMATION, CARDIOVASCULAR DISORDERS, RENAL DISEASES, OR AS CONTRACEPTIVES SANOFI (FR) 1999-04-06 US disclosed
US-5891893-A 5-AMINO-1,2,4-OXA(OR THIA)DIAZOLES; ANTAGONISTS OF PLATELET ACTIVATING FACTOR USEFUL IN TREATMENT OF ASTHMA, ALLERGIES, INFLAMMATION, CARDIOVASCULAR DISEASES, RENAL DISEASES, OR AS CONTRACEPTIVES SANOFI (FR) 1999-04-06 US disclosed
US-5780468-A ANTAGONIST OF PLATELET ACTIVATING FACTOR SANOFI (FR) 1998-07-14 US disclosed
WO-1998005630-A1 PROCESS FOR THE PREPARATION OF ORGANIC NITRILES ALLIEDSIGNAL INC. (US) 1998-02-12 WO disclosed
US-5470855-A Anticoagulants SANOFI (FR) 1995-11-28 US disclosed
US-4008264-A Process for the preparation of aromatic thiocarboxylic acid amides HOECHST AKTIENGESELLSCHAFT (DT) 1977-02-15 US disclosed
US-3948968-A COMPLEXING WITH PYRIDINES OR QUINOLINES, REACTION WITH AMMONIA MARATHON OIL COMPANY (US) 1976-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160046657-A1 ORGANOPALLADIUM COMPOUNDS AS POLYMERIZATION CATALYSTS MVD, DDT, CDV3 KDM4E 1705/4885ALDH1A1 1284/4885MAPT 3248/4885
US-20250129016-A1 PHOTOREDOX METHODS FOR RADIOCYANATION OF ARENES AND USE THEREOF RCC2, PPOX, FTO KDM4E 290/4885ALDH1A1 2660/4885MAPT 2387/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.