Aceglatone

Aceglatone

SCHEMBL8852

CC(=O)O[C@@H]1C(=O)O[C@@H]2[C@H]1OC(=O)[C@@H]2OC(C)=O

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.39
PRKCA P17252 4/20 0.35
PRKD3 O94806 3/20 0.35
PRKCG P05129 3/20 0.35
PRKCB P05771 3/20 0.35
PRKCH P24723 3/20 0.35
PRKCE Q02156 3/20 0.35
PRKCQ Q04759 3/20 0.35
PRKCD Q05655 3/20 0.35
PRKD1 Q15139 3/20 0.35
TAS2R46 P59540 2/20 0.32
ABCB1 P08183 1/20 0.31
CYP1A1 P04798 1/20 0.31
TSHR P16473 1/20 0.31
ALOX5 P09917 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aceglatone SCHEMBL3843289 0.82 ALDH1A1 (0.36) PRKCAPRKD3PRKCGPRKCBPRKCH
SCHEMBL9013173 0.80 OGA (0.38) POLBPRKCAPRKD3PRKCGPRKCB
SCHEMBL10719694 0.80 OGA (0.38) POLBPRKCAPRKD3PRKCGPRKCB
SCHEMBL9013175 0.80 OGA (0.38) POLBPRKCAPRKD3PRKCGPRKCB
SCHEMBL10339626 0.80 OGA (0.38) POLBPRKCAPRKD3PRKCGPRKCB
SCHEMBL1333553 0.76 POLB (0.42) POLBPRKCAPRKD3PRKCGPRKCB
SCHEMBL8220668 0.76 POLB (0.42) POLBPRKCAPRKD3PRKCGPRKCB
SCHEMBL52102 0.76 POLB (0.42) POLBPRKCAPRKD3PRKCGPRKCB
SCHEMBL7893349 0.76 POLB (0.42) POLBPRKCAPRKD3PRKCGPRKCB
SCHEMBL2480467 0.76 POLB (0.42) POLBPRKCAPRKD3PRKCGPRKCB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 22010 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4748859-A2 CHEMICALLY AND PHOTOCHEMICALLY INITIATED CELL MEMBRANE BLEBBING TO INDUCE CELL VESICLE PRODUCTION, MODIFICATIONS THEREOF, AND USES THEREOF The Regents of the University of California (US) 2026-05-27 EP claimed
US-20260137794-A1 LIGAND-DRUG CONJUGATE AND USE THEREOF SYSTIMMUNE INC (US) 2026-05-21 US claimed
EP-4743490-A1 HUMANIZED ANTI-CD7 ANTIBODY Christian-Albrechts-Universität zu Kiel (DE) 2026-05-20 EP claimed
WO-2026099502-A1 NOVEL DRUG CONJUGATES FOR TESTING CELLULAR DRUG UPTAKE Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) 2026-05-15 WO claimed
US-20260108619-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2026-04-23 US claimed
US-20260085100-A1 METHODS OF ANTIGEN PRODUCTION THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY (US) 2026-03-26 US claimed
US-12576124-B2 Formulation of a conjugate of a tubulysin analog to a cell-binding molecule HANGZHOU DAC BIOTECH CO., LTD (CN) 2026-03-17 US claimed
EP-4698185-A1 METHODS AND SYSTEMS FOR IMPROVING ANTI-CANCER THERAPIES Osasuna Therapeutics SA (CH) 2026-02-25 EP claimed
EP-4694909-A1 METHODS OF MODULATING THE EPITHELIAL-MESENCHYMAL TRANSITION RS Oncology, LLC (US) 2026-02-18 EP claimed
EP-4687999-A1 TROP2 CONJUGATED BIOLOGICAL MOLECULES, PHARMACEUTICAL COMPOSITIONS AND METHODS OBI Pharma, Inc. (TW) 2026-02-11 EP claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000054795-A1 COMBINED THERAPY WITH A CHEMOTHERAPEUTIC AGENT AND AN ONCOLYTIC VIRUS FOR KILLING TUMOR CELLS IN A SUBJECT THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2000-09-21 WO claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
CN-1261803-A Antioxidant enhancement of therapy for hyperproliferative conditions ATHEROGENICS INC (US) 2000-08-02 CN claimed
EP-1019034-A2 ANTIOXIDANT ENHANCEMENT OF THERAPY FOR HYPERPROLIFERATIVE CONDITIONS Atherogenics, Inc. (US) 2000-07-19 EP claimed
WO-2000040269-A2 PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF DISEASED TISSUES LEE CLARENCE C (US) 2000-07-13 WO claimed
WO-1999001118-A9 ANTIOXIDANT ENHANCEMENT OF THERAPY FOR HYPERPROLIFERATIVE CONDITIONS ATHEROGENICS INC (US) 1999-05-20 WO claimed
WO-1999001118-A2 ANTIOXIDANT ENHANCEMENT OF THERAPY FOR HYPERPROLIFERATIVE CONDITIONS ATHEROGENICS, INC. (US) 1999-01-14 WO claimed
EP-0875246-A1 Pharmaceutical preparation of ascorbic acid derivatives for medical treatment of cancer SHOWA DENKO KABUSHIKI KAISHA (JP) 1998-11-04 EP claimed
US-5811547-A Method for inducing crystalline state transition in medicinal substance NIPPON SHINYAJU CO., LTD. (JP) 1998-09-22 US claimed