Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.47 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 10/20 | 0.44 |
| ▸ | TOP2A | P11388 | 3/20 | 0.44 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9231645 | 0.86 | MEN1 (0.36) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL8851657 | 0.81 | MEN1 (0.59) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL8327189 | 0.81 | MEN1 (0.54) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL9083171 | 0.79 | POLB (0.58) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL9376194 | 0.79 | TOP2A (0.56) | MEN1KMT2AKCNH2POLBTOP2A | |
| Hydrochloric Acid SCHEMBL8852523 | 0.79 | POLB (0.58) | MEN1KMT2AKCNH2POLBCACNA1F | |
| Hydrochloric Acid SCHEMBL9837318 | 0.78 | TOP2A (0.55) | MEN1KMT2AKCNH2POLBTOP2A | |
| SCHEMBL8851667 | 0.78 | MEN1 (0.52) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL8852040 | 0.77 | MEN1 (0.54) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL9868270 | 0.77 | CACNA1F (0.63) | MEN1KMT2AKCNH2POLBCACNA1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5659038-A | GRAMPOSITIVE/GRAMNEGATIVE MICROBIOCIDES; ANTISEPTICS, HUMAN AND VETERINARY MEDICINE | BAYER AKTIENGESELLSCHAFT (DE) | 1997-08-19 | — | — | US | disclosed |
| US-5578604-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-11-26 | — | — | US | disclosed |
| EP-0671391-A1 | 5-Vinyl- and 5-ethinyl-quinolinone- and -naphthyridone-carboxylic acids | BAYER AG (DE) | 1995-09-13 | — | — | EP | disclosed |