Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.34 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.32 |
| ▸ | TOP2A | P11388 | 2/20 | 0.32 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8852463 | 0.86 | MEN1 (0.50) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL9233385 | 0.82 | MEN1 (0.43) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL8327191 | 0.82 | MEN1 (0.37) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL9231288 | 0.80 | POLB (0.47) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL9376199 | 0.80 | TOP2A (0.42) | MEN1KMT2AKCNH2POLBTOP2A | |
| SCHEMBL9234530 | 0.79 | ALDH1A1 (0.42) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL9233062 | 0.76 | MEN1 (0.38) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL9669417 | 0.76 | ALDH1A1 (0.49) | MEN1KMT2AKCNH2POLBTOP2A | |
| SCHEMBL9231698 | 0.76 | MEN1 (0.52) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL9196441 | 0.75 | KDM4E (0.51) | MEN1KMT2AKCNH2POLBGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587491-A | Method for the synthesis of bis-tetrahydrofuranyl Annonaceous acetogenins | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1996-12-24 | — | — | US | disclosed |