Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 8/20 | 0.52 |
| ▸ | MAOA | P21397 | 7/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.42 |
| ▸ | CDK1 | P06493 | 2/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.42 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.42 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16130067 | 0.82 | DYRK1A (0.52) | DYRK1AMAOACCNB2CDK1CCNB1 | |
| SCHEMBL2780628 | 0.80 | DYRK1A (0.58) | DYRK1AMAOACCNB2CDK1CCNB1 | |
| SCHEMBL30939928 | 0.77 | CCNB2 (0.68) | DYRK1AMAOACCNB2CDK1CCNB1 | |
| SCHEMBL177685 | 0.77 | CCNB2 (0.68) | DYRK1AMAOACCNB2CDK1CCNB1 | |
| Hydrochloric Acid SCHEMBL647417 | 0.76 | CCNB2 (0.66) | DYRK1AMAOACCNB2CDK1CCNB1 | |
| Hydrochloric Acid SCHEMBL3769079 | 0.74 | CCNB2 (0.64) | DYRK1AMAOACCNB2CDK1CCNB1 | |
| Hydrochloric Acid SCHEMBL970432 | 0.74 | CCNB2 (0.64) | DYRK1AMAOACCNB2CDK1CCNB1 | |
| SCHEMBL16123490 | 0.73 | DYRK1A (0.53) | DYRK1AMAOACCNB2CDK1CCNB1 | |
| SCHEMBL3182013 | 0.71 | DYRK1A (0.55) | DYRK1AMAOACCNB2CDK1CCNB1 | |
| SCHEMBL30940005 | 0.70 | DYRK1A (0.65) | DYRK1AMAOACCNB2CDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591738-A | Method of treating chemical dependency using β-carboline alkaloids, derivatives and salts thereof | NDA INTERNATIONAL, INC. (US) | 1997-01-07 | — | — | US | claimed |