⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9510274 | 0.84 | — | — | |
| SCHEMBL9506360 | 0.81 | KMT2A (0.36) | — | |
| SCHEMBL8848006 | 0.76 | — | — | |
| SCHEMBL10711247 | 0.69 | OPRM1 (0.31) | — | |
| SCHEMBL11384739 | 0.67 | ADRA2C (0.38) | — | |
| SCHEMBL9874264 | 0.66 | ADRA2C (0.37) | — | |
| SCHEMBL30492788 | 0.66 | — | — | |
| SCHEMBL11385949 | 0.65 | ADRA2C (0.39) | — | |
| SCHEMBL28875760 | 0.62 | CYP3A4 (0.32) | — | |
| SCHEMBL11392361 | 0.62 | ADRA2C (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0104495-B1 | COMPOUNDS HAVING AN ANTIDOTE ACTIVITY FOR THE PROTECTION OF CULTIVATIONS OF AGRARIAN INTEREST FROM THE ACTION OF NONSELECTIVE HERBICIDES | Montedison S.p.A. (IT) | 1988-11-30 | — | — | EP | claimed |
| US-4628101-A | PLANT SAFENING AGENTS | MONTEDISON S.P.A. (IT) | 1986-12-09 | — | — | US | claimed |
| EP-0104495-A2 | Compounds having an antidote activity for the protection of cultivations of agrarian interest from the action of nonselective herbicides | Montedison S.p.A. (IT) | 1984-04-04 | — | — | EP | claimed |
| US-5691274-A | PLANT SAFTENING AGENTS FOR HERBICIDES | ZENECA LIMITED (GB) | 1997-11-25 | — | — | US | disclosed |
| US-5527761-A | MIXTURE OF ISOXAZOLIDINONES, DICHLOROACETAMIDES, TRIAZINE, TOLUIDINE AND SULFONYLUREA HERBICIDES | ZENECA LIMITED (GB) | 1996-06-18 | — | — | US | disclosed |
| US-5527762-A | AMIDES OF HALOALKANOIC ACIDS, INCLUDING OXAZOLIDINES AND THIOZOLIDIENS USED AS NON-PHYTOTOXIC ANTIDOTES | ZENECA LIMITED (GB) | 1996-06-18 | — | — | US | disclosed |
| US-5395816-A | Antidoting herbicidal 3-ixoxazolidinone compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1995-03-07 | — | — | US | disclosed |
| EP-0561970-B1 | ANTIDOTING HERBICIDAL 3-ISOXAZOLIDINONE COMPOUNDS | ZENECA INC (US) | 1995-01-18 | — | — | EP | disclosed |
| EP-0561970-A1 | ANTIDOTING HERBICIDAL 3-ISOXAZOLIDINONE COMPOUNDS. | ZENECA INC (US) | 1993-09-29 | — | — | EP | disclosed |
| WO-1992010095-A1 | ANTIDOTING HERBICIDAL 3-ISOXAZOLIDINONE COMPOUNDS | ZENECA INC. (US) | 1992-06-25 | — | — | WO | disclosed |
| US-5051125-A | S-ethyl cyclohexylethyl thiocarbamate and 2-chloro-4-(ethylamino)-6-(2-cyanoisopropylamino)-s-triazine | ICI AMERICAS INC. (US) | 1991-09-24 | — | — | US | disclosed |
| EP-0104495-B1 | COMPOUNDS HAVING AN ANTIDOTE ACTIVITY FOR THE PROTECTION OF CULTIVATIONS OF AGRARIAN INTEREST FROM THE ACTION OF NONSELECTIVE HERBICIDES | Montedison S.p.A. (IT) | 1988-11-30 | — | — | EP | disclosed |
| US-4628101-A | PLANT SAFENING AGENTS | MONTEDISON S.P.A. (IT) | 1986-12-09 | — | — | US | disclosed |
| EP-0184870-A1 | Synergistic herbicidal composition | STAUFFER CHEMICAL COMPANY (US) | 1986-06-18 | — | — | EP | disclosed |
| EP-0104495-A2 | Compounds having an antidote activity for the protection of cultivations of agrarian interest from the action of nonselective herbicides | Montedison S.p.A. (IT) | 1984-04-04 | — | — | EP | disclosed |