Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 17/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.44 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8458897 | 1.00 | REN (0.45) | RENCACNA1BCPB2 | |
| SCHEMBL7436803 | 0.91 | REN (0.45) | REN | |
| SCHEMBL7436801 | 0.91 | REN (0.45) | REN | |
| SCHEMBL8853027 | 0.90 | REN (0.47) | REN | |
| SCHEMBL8458848 | 0.90 | REN (0.47) | REN | |
| SCHEMBL7431276 | 0.89 | REN (0.44) | REN | |
| SCHEMBL7431278 | 0.89 | REN (0.44) | REN | |
| SCHEMBL8853182 | 0.86 | CACNA1B (0.38) | RENCACNA1BCPB2 | |
| SCHEMBL8458792 | 0.86 | REN (0.57) | RENCACNA1B | |
| SCHEMBL8462589 | 0.86 | REN (0.57) | RENCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663200-A | CARBAMOYL PEPTIDE DERIVATIVES AS VIRICIDES | CIBA-GEIGY CORPORATION (US) | 1997-09-02 | — | — | US | disclosed |
| EP-0708085-A2 | Antiviral ethers of aspartate protease substrate isosteres | CIBA-GEIGY AG (CH) | 1996-04-24 | — | — | EP | disclosed |