Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 19/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7436801 | 1.00 | REN (0.45) | RENCTSSCTSK | |
| SCHEMBL8853149 | 0.91 | REN (0.45) | REN | |
| SCHEMBL8458897 | 0.91 | REN (0.45) | REN | |
| SCHEMBL7431278 | 0.90 | REN (0.44) | RENCTSSCTSK | |
| SCHEMBL7431276 | 0.90 | REN (0.44) | RENCTSSCTSK | |
| SCHEMBL7426534 | 0.88 | CTSS (0.47) | CTSSCTSK | |
| SCHEMBL7426537 | 0.88 | CTSS (0.47) | CTSSCTSK | |
| SCHEMBL8458848 | 0.88 | REN (0.47) | REN | |
| SCHEMBL8853027 | 0.88 | REN (0.47) | REN | |
| SCHEMBL7435053 | 0.85 | CTSS (0.45) | CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643878-A | TREATMENT OF RETROVIRAL DISEASES LIKE AIDS | CIBA-GEIGY CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |
| EP-0532466-A2 | Derivatives of 5-amino-4-hydroxy-hexanoic acid and their therapeutical use | CIBA-GEIGY AG (CH) | 1993-03-17 | — | — | EP | disclosed |