Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | CES2 | O00748 | 1/20 | 0.66 |
| ▸ | CES1 | P23141 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16653010 | 0.86 | LMNA (0.54) | LMNACES2CES1TSHRALDH1A1 | |
| SCHEMBL16653006 | 0.86 | LMNA (0.54) | LMNACES2CES1TSHRALDH1A1 | |
| SCHEMBL2299624 | 0.85 | PARP10 (0.56) | LMNACES2CES1TSHRALDH1A1 | |
| Benzoin SCHEMBL21065805 | 0.85 | LMNA (0.72) | LMNACES2CES1TSHRALDH1A1 | |
| SCHEMBL30887385 | 0.85 | PARP10 (0.56) | LMNACES2CES1TSHRALDH1A1 | |
| Benzoin SCHEMBL9512884 | 0.85 | LMNA (0.72) | LMNACES2CES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL30282 | 0.85 | LMNA (0.72) | LMNACES2CES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL16649153 | 0.85 | LMNA (0.72) | LMNACES2CES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL4576093 | 0.85 | LMNA (0.72) | LMNACES2CES1TSHRALDH1A1 | |
| Benzoin SCHEMBL28085464 | 0.85 | LMNA (0.72) | LMNACES2CES1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629358-A | Photocurable resin composition containing acrylate silane and epoxy silane and/or their hydrolysis products | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1997-05-13 | — | — | US | disclosed |
| EP-0549228-B1 | Photocurable resin composition | NAT STARCH CHEM INVEST (US) | 1996-08-28 | — | — | EP | disclosed |
| EP-0549228-A2 | Photocurable resin composition | National Starch and Chemical Investment Holding Corporation (US) | 1993-06-30 | — | — | EP | disclosed |