Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4463424 | 0.71 | TSHR (0.50) | TSHRUSP2HTTNPSR1CA1 | |
| SCHEMBL5686223 | 0.67 | — | — | |
| SCHEMBL6871426 | 0.64 | — | — | |
| SCHEMBL12864235 | 0.64 | — | — | |
| SCHEMBL16590590 | 0.64 | TSHR (0.52) | TSHRUSP2HTTNPSR1CA1 | |
| SCHEMBL8174142 | 0.62 | — | — | |
| SCHEMBL13609174 | 0.62 | TSHR (0.71) | TSHRUSP2HTTNPSR1CA1 | |
| SCHEMBL22176551 | 0.62 | — | — | |
| SCHEMBL7067275 | 0.62 | — | — | |
| SCHEMBL9508527 | 0.62 | TSHR (0.56) | TSHRUSP2HTTNPSR1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468663-B1 | Room temperature curing composition | SHINETSU CHEMICAL CO (JP) | 1997-09-17 | — | — | EP | disclosed |
| US-5326816-A | Sealants, coatings, soil release, polymer with repeating disiloxane group | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1994-07-05 | — | — | US | disclosed |
| US-5177131-A | Polysilethylenesiloxane, hydrolyzable silane compound | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1993-01-05 | — | — | US | disclosed |
| EP-0468663-A2 | Room temperature curing composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1992-01-29 | — | — | EP | disclosed |