Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 7/20 | 0.61 |
| ▸ | CREBBP | Q92793 | 7/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9287395 | 0.90 | BRD4 (0.57) | BRD4CREBBPHSD17B10ALDH1A1TSHR | |
| SCHEMBL8853215 | 0.89 | BRD4 (0.56) | BRD4CREBBPHSD17B10ALDH1A1TSHR | |
| SCHEMBL8853794 | 0.88 | BRD4 (0.65) | BRD4CREBBPHSD17B10ALDH1A1TSHR | |
| SCHEMBL9628743 | 0.86 | BRD4 (0.51) | BRD4CREBBPHSD17B10ALDH1A1TSHR | |
| SCHEMBL30583054 | 0.78 | HSD17B10 (0.59) | BRD4CREBBPHSD17B10ALDH1A1TSHR | |
| SCHEMBL9629704 | 0.77 | BRD4 (0.55) | BRD4CREBBPHSD17B10ALDH1A1TSHR | |
| SCHEMBL9629592 | 0.77 | BRD4 (0.54) | BRD4CREBBPHSD17B10ALDH1A1TSHR | |
| SCHEMBL8853797 | 0.76 | CREBBP (1.00) | BRD4CREBBPHSD17B10ALDH1A1TSHR | |
| SCHEMBL9629696 | 0.74 | CREBBP (0.71) | BRD4CREBBPHSD17B10ALDH1A1TSHR | |
| SCHEMBL5671154 | 0.74 | HSD17B10 (0.61) | HSD17B10ALDH1A1TSHRSMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60032778-A | — | — | None | — | — | JP | disclosed |
| EP-0657407-B1 | Process for the preparation of 3-fluoro-4,6-dichlorotoluene | BAYER AG (DE) | 1997-12-10 | — | — | EP | disclosed |
| US-5475164-A | Process for preparing 3-fluoro-4,6-dichlorotoluene | BAYER AKTIENGESELLSCHAFT (DE) | 1995-12-12 | — | — | US | disclosed |
| EP-0657407-A1 | Process for the preparation of 3-fluoro-4,6-dichlorotoluene | BAYER AG (DE) | 1995-06-14 | — | — | EP | disclosed |
| US-5105036-A | Friedel-Crafts catalyst and oxy-substituted cyclic amidines as cocatylsts; preferential formation of p-isomer | BAYER AKTIENGESELLSCHAFT (DE) | 1992-04-14 | — | — | US | disclosed |
| EP-0292824-B1 | PROCESS FOR THE NUCLEAR CHLORINATION OF AROMATIC HYDROCARBONS | BAYER AG (DE) | 1990-08-01 | — | — | EP | disclosed |
| US-4851596-A | Process for nucleus-chlorination of aromatic hydrocarbons | BAYER AKTIENGESELLSCHAFT (DE) | 1989-07-25 | — | — | US | disclosed |
| EP-0292824-A1 | Process for the nuclear chlorination of aromatic hydrocarbons | BAYER AG (DE) | 1988-11-30 | — | — | EP | disclosed |
| JP-S6032778-A | 1,5-BENZOTHIAZEPINE DERIVATIVE, ITS PREPARATION, AND CONTROLLER FOR PLANT BLIGHT COMPRISING IT AS ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD | 1985-02-19 | — | — | JP | disclosed |