Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 9/20 | 0.71 |
| ▸ | BRD4 | O60885 | 8/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | EP300 | Q09472 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8853797 | 0.83 | CREBBP (1.00) | CREBBPBRD4ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL11069336 | 0.77 | BRD4 (0.66) | CREBBPBRD4ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL10353037 | 0.77 | BRD4 (0.66) | CREBBPBRD4ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL8853794 | 0.76 | BRD4 (0.65) | CREBBPBRD4ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL9629698 | 0.75 | CREBBP (0.64) | CREBBPBRD4ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL9817819 | 0.75 | ALDH1A1 (1.00) | CREBBPBRD4ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL8853752 | 0.75 | CREBBP (0.54) | CREBBPBRD4ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL9629512 | 0.74 | BRD4 (0.71) | CREBBPBRD4ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL8853387 | 0.74 | BRD4 (0.61) | CREBBPBRD4ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL8853822 | 0.73 | MEN1 (0.44) | CREBBPBRD4ALDH1A1HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0340581-B1 | PROCESS FOR THE CHLORINATION IN THE NUCLEUS OF AROMATIC HYDROCARBONS | BAYER AG (DE) | 1992-03-18 | — | — | EP | disclosed |
| US-4925994-A | Process for the ring chlorination of aromatic hydrocarbons | BAYER AKTIENGESELLSCHAFT (DE) | 1990-05-15 | — | — | US | disclosed |
| EP-0340581-A2 | Process for the chlorination in the nucleus of aromatic hydrocarbons | BAYER AG (DE) | 1989-11-08 | — | — | EP | disclosed |