Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.54 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9628743 | 0.89 | BRD4 (0.51) | BRD4CREBBPHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL8853794 | 0.85 | BRD4 (0.65) | BRD4CREBBPHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL9629512 | 0.80 | BRD4 (0.71) | BRD4CREBBPHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL9630779 | 0.77 | BRD4 (0.54) | BRD4CREBBPHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL8853387 | 0.77 | BRD4 (0.61) | BRD4CREBBPHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL9628805 | 0.76 | HSD17B10 (0.72) | BRD4CREBBPHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL9287395 | 0.73 | BRD4 (0.57) | BRD4CREBBPHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL8853215 | 0.72 | BRD4 (0.56) | BRD4CREBBPHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL8524142 | 0.71 | CRBN (0.46) | BRD4CREBBPALDH1A1HTTNPC1 | |
| SCHEMBL5671626 | 0.70 | HSD17B10 (0.65) | HSD17B10ALDH1A1SMN1; SMN2TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0340581-B1 | PROCESS FOR THE CHLORINATION IN THE NUCLEUS OF AROMATIC HYDROCARBONS | BAYER AG (DE) | 1992-03-18 | — | — | EP | disclosed |
| US-4925994-A | Process for the ring chlorination of aromatic hydrocarbons | BAYER AKTIENGESELLSCHAFT (DE) | 1990-05-15 | — | — | US | disclosed |
| EP-0340581-A2 | Process for the chlorination in the nucleus of aromatic hydrocarbons | BAYER AG (DE) | 1989-11-08 | — | — | EP | disclosed |