Methacrylic Acid

Methacrylic Acid

SCHEMBL8853404

C=C(C)C(=O)O.C=C(C)C(=O)O.CC.COC

nearest known ligand 0.50

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Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
TDP1 Q9NUW8 2/20 0.42
HSD17B10 Q99714 1/20 0.38
FFAR3 O14843 1/20 0.38
LCK P06239 1/20 0.38
FYN P06241 1/20 0.38
MAPT P10636 1/20 0.34
TSHR P16473 4/20 0.33
PEPD P12955 1/20 0.32
LMNA P02545 1/20 0.31
THRB P10828 1/20 0.31
MGAM O43451 1/20 0.30
GAA P10253 1/20 0.30
SI P14410 1/20 0.30
MGAM2 Q2M2H8 1/20 0.30
TGFBR1 P36897 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL285672 0.97
Methacrylic Acid SCHEMBL23699842 0.97 ALDH1A1 (0.53) ALDH1A1TDP1HSD17B10FFAR3LCK
Methacrylic Acid SCHEMBL27961530 0.93 ALDH1A1 (0.50) ALDH1A1TDP1HSD17B10FFAR3LCK
Methacrylic Acid SCHEMBL20334967 0.93 ALDH1A1 (0.50) ALDH1A1TDP1HSD17B10FFAR3LCK
Methacrylic Acid SCHEMBL15312521 0.93 ALDH1A1 (0.50) ALDH1A1TDP1HSD17B10FFAR3LCK
Methacrylic Acid SCHEMBL28138837 0.89 TDP1 (0.50) ALDH1A1TDP1HSD17B10FFAR3LCK
Methacrylic Acid SCHEMBL698492 0.89
Methacrylic Acid SCHEMBL2802554 0.89 TDP1 (0.50) ALDH1A1TDP1HSD17B10FFAR3LCK
Methacrylic Acid SCHEMBL4087526 0.89 TDP1 (0.50) ALDH1A1TDP1HSD17B10FFAR3LCK
Methacrylic Acid SCHEMBL3621685 0.89 TDP1 (0.50) ALDH1A1TDP1HSD17B10FFAR3LCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0397091-B1 Methacrylic resin compositions with improved tacky adhesion and method for preparation thereof KURARAY CO (JP) 1997-02-26 EP disclosed
US-5294676-A Crosslinked alkyl methacrylate polymer dissolved in its syrup; heat resistant automobile moldings; coverings KURARAY CO., LTD. (JP) 1994-03-15 US disclosed
EP-0158478-B1 METHACRYLIC RESIN MOLDING MATERIAL AND METHOD FOR PRODUCTION THEREOF Kuraray Co., Ltd. (JP) 1992-07-22 EP disclosed
EP-0397091-A2 Methacrylic resin compositions with improved tacky adhesion and method for preparation thereof KURARAY CO., LTD. (JP) 1990-11-14 EP disclosed
US-4791184-A PARTIALLY CROSSLINKED GEL BY STOICHIOMETRIC CONTROL OF THE INITIATED POLYMERIZATION OF METHACRYLATE AND CROSSLINKING AGENT; HEAT AND SOLVENT RESISTANCE KYOWA GAS CHEMICAL INDUSTRY CO., LTD. (JP) 1988-12-13 US disclosed
EP-0158478-A2 Methacrylic resin molding material and method for production thereof Kuraray Co., Ltd. (JP) 1985-10-16 EP disclosed