Acrylic Acid

Acrylic Acid

SCHEMBL8853534

C=C(C)C(=O)OCC(O)CCl.C=CC(=O)O

nearest known ligand 0.49

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Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.49
THRB P10828 1/20 0.35
ALDH1A1 P00352 3/20 0.33
USP2 O75604 1/20 0.33
CYP3A4 P08684 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
LMNA P02545 1/20 0.32
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31
POLB P06746 1/20 0.30
APEX1 P27695 1/20 0.30
HTT P42858 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL9818657 0.90 TSHR (0.55) TSHRTHRBALDH1A1USP2CYP3A4
SCHEMBL129034 0.90 TSHR (0.59) TSHRTHRBALDH1A1USP2CYP3A4
SCHEMBL28832982 0.88 TSHR (0.57) TSHRTHRBALDH1A1USP2CYP3A4
Acrylic Acid SCHEMBL28379137 0.86 USP2 (0.33) TSHRALDH1A1USP2CYP3A4MAPT
Acrylic Acid SCHEMBL6982262 0.85 TSHR (0.50) TSHRTHRBALDH1A1USP2CYP3A4
Trimethylammonium SCHEMBL5577122 0.85 TSHR (0.53) TSHRTHRBALDH1A1
Acrylic Acid SCHEMBL28639653 0.84 TSHR (0.49) TSHRTHRBALDH1A1USP2CYP3A4
Acrylic Acid SCHEMBL28165263 0.84 TSHR (0.49) TSHRTHRBALDH1A1USP2CYP3A4
SCHEMBL28190290 0.83 TSHR (0.52) TSHRTHRBALDH1A1MAPTSMN1; SMN2
Acrylic Acid SCHEMBL2354185 0.83 TSHR (0.60) TSHRTHRBALDH1A1USP2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0397091-B1 Methacrylic resin compositions with improved tacky adhesion and method for preparation thereof KURARAY CO (JP) 1997-02-26 EP disclosed