Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10535054 | 0.82 | SMN1; SMN2 (0.45) | SMN1; SMN2L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL5524988 | 0.81 | SMN1; SMN2 (0.39) | SMN1; SMN2L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL7706526 | 0.81 | SMN1; SMN2 (0.40) | SMN1; SMN2L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL411806 | 0.80 | SMN1; SMN2 (0.42) | SMN1; SMN2L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL28515317 | 0.76 | SMN1; SMN2 (0.40) | SMN1; SMN2L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL13858310 | 0.75 | SMN1; SMN2 (0.41) | SMN1; SMN2L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL2783538 | 0.75 | SMN1; SMN2 (0.41) | SMN1; SMN2L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL6508549 | 0.75 | SMN1; SMN2 (0.41) | SMN1; SMN2L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL6925024 | 0.75 | SMN1; SMN2 (0.41) | SMN1; SMN2L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL6925032 | 0.75 | SMN1; SMN2 (0.41) | SMN1; SMN2L3MBTL1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0493767-B1 | Synergistic combination for treating herpes infections | BIO MEGA BOEHRINGER INGELHEIM (CA) | 1997-03-19 | — | — | EP | disclosed |
| US-5484771-A | RIBONUCLEOTIDE REDUCTASE INHIBITORS | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1996-01-16 | — | — | US | disclosed |
| EP-0461546-B1 | Antiherpes peptide derivatives having a 1,4-dioxo-C4 N-terminus | BIO MEGA BOEHRINGER INGELHEIM (CA) | 1995-03-22 | — | — | EP | disclosed |
| US-5380727-A | Antiviral nucleoside analog and a ribonucleotide reductase inhibiting peptide derivative | BIO-MEGA, INC. (CA) | 1995-01-10 | — | — | US | disclosed |
| EP-0493767-A2 | Synergistic combination for treating herpes infections | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1992-07-08 | — | — | EP | disclosed |
| EP-0461546-A2 | Antiherpes peptide derivatives having a 1,4-dioxo-C4 N-terminus | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1991-12-18 | — | — | EP | disclosed |