SCHEMBL8854496

SCHEMBL8854496

[CH2]OS(=O)(=O)c1c(F)cccc1OC(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 1/20 0.36
KDM4E B2RXH2 1/20 0.35
PKM P14618 1/20 0.35
PKLR P30613 1/20 0.35
SLC40A1 Q9NP59 1/20 0.33
EPHX2 P34913 1/20 0.33
KAT6A Q92794 1/20 0.32
MPL P40238 1/20 0.32
EPAS1 Q99814 1/20 0.31
RORC P51449 2/20 0.31
SCN9A Q15858 1/20 0.31
SCN10A Q9Y5Y9 1/20 0.31
GRIA1 P42261 1/20 0.31
CACNG8 Q8WXS5 1/20 0.31
ALPL P05186 1/20 0.31
TRPA1 O75762 1/20 0.31
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
HTR2B P41595 1/20 0.31
FABP4 P15090 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8854502 0.84 KCNN4 (0.36) KCNN4KDM4EPKMPKLRSLC40A1
SCHEMBL16467626 0.80 PKM (0.45) PKMPKLRSLC40A1PTGES2
SCHEMBL8412334 0.80 KCNK3 (0.37) KCNN4KDM4EPKMPKLRSLC40A1
SCHEMBL8412716 0.80 PKM (0.37) KCNN4KDM4EPKMPKLRSLC40A1
SCHEMBL8412600 0.79 PKM (0.36) KCNN4KDM4EPKMPKLRSLC40A1
SCHEMBL8412605 0.79 EPHX2 (0.36) KCNN4KDM4EPKMPKLRSLC40A1
SCHEMBL8854439 0.77 KCNN4 (0.33) KCNN4PKMPKLRGRIA1CACNG8
SCHEMBL8854595 0.77 KCNN4 (0.33) KCNN4PKMPKLR
SCHEMBL8854543 0.76 KCNN4 (0.32) KCNN4KDM4ESLC40A1KAT6AFABP4
SCHEMBL8854518 0.76 KCNN4 (0.32) KCNN4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5693590-A PLANT GROWTH REGULATOR ROHM AND HAAS COMPANY (US) 1997-12-02 US claimed