Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 4/20 | 0.37 |
| ▸ | KCNK9 | Q9NPC2 | 4/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PKLR | P30613 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.30 |
| ▸ | F2R | P25116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8409594 | 0.85 | KCNK3 (0.37) | KCNK3KCNK9SLC40A1KDM4EF2R | |
| SCHEMBL8854502 | 0.83 | KCNN4 (0.36) | KCNK3KCNK9KCNN4HCRTR1HCRTR2 | |
| SCHEMBL8411219 | 0.83 | KCNK3 (0.36) | KCNK3KCNK9HCRTR1HCRTR2EPHX2 | |
| SCHEMBL14114762 | 0.82 | PKM (0.41) | PKMPKLRSLC40A1KAT6A | |
| SCHEMBL8854496 | 0.80 | KCNN4 (0.36) | KCNN4PKMPKLRSLC40A1KDM4E | |
| SCHEMBL8732363 | 0.79 | KCNK3 (0.34) | KCNK3KCNK9HCRTR1HCRTR2F2R | |
| SCHEMBL8735695 | 0.78 | KCNK3 (0.33) | KCNK3KCNK9HCRTR1HCRTR2 | |
| SCHEMBL8409554 | 0.77 | SLC22A12 (0.41) | KCNK3KCNK9SLC40A1 | |
| SCHEMBL8732023 | 0.77 | KCNK3 (0.33) | KCNK3KCNK9HCRTR1HCRTR2F2R | |
| SCHEMBL8412812 | 0.76 | ACHE (0.38) | PKMPKLRKAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1339432-A | Extracting method for substituted phenyl compounds | ROHM & HAAS (US) | 2002-03-13 | — | — | CN | disclosed |
| CN-1070175-C | Process for the preparation of 2, 6-disubstituted benzenesulfonates or 2, 6-disubstituted benzenesulfonates further substituted in the 3-, 4-or 5-position | ROHM & HAAS (US) | 2001-08-29 | — | — | CN | disclosed |
| EP-0708087-B1 | Method for making a substituted benzene compound | ROHM & HAAS (US) | 1999-07-28 | — | — | EP | disclosed |
| CN-1174189-A | Process for preparing substituted benzene compounds | ROHM & HAAS (US) | 1998-02-25 | — | — | CN | disclosed |
| US-5670691-A | REACTION OF 2-SUBSTITUTED BENZENESULFONATE WITH LITHIUM COMPOUND THEN REACTION WITH ELECTROPHILE TO FORM 2,6-DISUBSTITUTED BENZENESULFONATE | ROHM AND HAAS COMPANY (US) | 1997-09-23 | — | — | US | disclosed |
| EP-0708087-A1 | Method for making a substituted benzene compound | ROHM AND HAAS COMPANY (US) | 1996-04-24 | — | — | EP | disclosed |