Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.35 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 4/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | PKLR | P30613 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.31 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8854443 | 0.86 | SLC22A12 (0.33) | SLC22A12PTGES2KIF11PKMPKLR | |
| SCHEMBL8854538 | 0.86 | MEN1 (0.35) | MEN1CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL8854611 | 0.83 | GABRA1 (0.35) | MEN1CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL8854595 | 0.81 | KCNN4 (0.33) | PKMPKLR | |
| SCHEMBL8854436 | 0.80 | KCNK3 (0.39) | NFE2L2KMT2A | |
| SCHEMBL8854622 | 0.78 | KEAP1 (0.33) | PKMPKLRKAT6A | |
| SCHEMBL8854719 | 0.78 | KMT2A (0.44) | SLC22A12HSD11B1MEN1KMT2A | |
| SCHEMBL8854454 | 0.77 | SLC22A12 (0.35) | SLC22A12PTGES2KIF11PKMPKLR | |
| SCHEMBL8854659 | 0.74 | — | — | |
| SCHEMBL8730124 | 0.73 | SLC22A12 (0.34) | SLC22A12PTGES2PKMPKLRNFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693590-A | PLANT GROWTH REGULATOR | ROHM AND HAAS COMPANY (US) | 1997-12-02 | — | — | US | claimed |