Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 20/20 | 0.48 |
| ▸ | PDE4A | P27815 | 19/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 19/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 19/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7419008 | 0.89 | PDE4B (0.61) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL11091127 | 0.81 | PDE4B (0.54) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7416606 | 0.80 | PDE4B (0.60) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7467100 | 0.78 | PDE4B (0.49) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7420726 | 0.78 | PDE4B (0.57) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL8357212 | 0.76 | PDE4A (0.70) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7466462 | 0.76 | PDE4A (0.51) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL5703617 | 0.75 | PDE4A (0.68) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL8360415 | 0.74 | PDE4A (0.67) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL9121794 | 0.74 | PDE4B (0.61) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5631286-A | Compounds useful for treating allergic or inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-20 | — | — | US | disclosed |