Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | LTA4H | P09960 | 6/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.58 |
| ▸ | ACHE | P22303 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.54 |
| ▸ | BAX | Q07812 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL425356 | 0.97 | HTT (0.69) | HTTSMN1; SMN2LTA4HTSHRTEAD4 | |
| SCHEMBL12355 | 0.97 | HTT (0.69) | HTTSMN1; SMN2LTA4HTSHRTEAD4 | |
| SCHEMBL17081753 | 0.97 | HTT (0.69) | HTTSMN1; SMN2LTA4HTSHRTEAD4 | |
| Diphenylether SCHEMBL19206965 | 0.95 | LTA4H (0.71) | HTTSMN1; SMN2LTA4HTSHRTEAD4 | |
| Diphenylether SCHEMBL9008689 | 0.95 | LTA4H (0.71) | HTTSMN1; SMN2LTA4HTSHRTEAD4 | |
| SCHEMBL24322042 | 0.90 | HTT (0.62) | HTTSMN1; SMN2LTA4HTSHRTEAD4 | |
| SCHEMBL20419433 | 0.90 | HTT (0.62) | HTTSMN1; SMN2LTA4HTSHRTEAD4 | |
| Trimethylammonium SCHEMBL27576820 | 0.90 | HTT (0.62) | HTTSMN1; SMN2LTA4HTSHRTEAD4 | |
| SCHEMBL822790 | 0.90 | HTT (0.62) | HTTSMN1; SMN2LTA4HTSHRTEAD4 | |
| SCHEMBL16741276 | 0.88 | SMN1; SMN2 (0.60) | HTTSMN1; SMN2LTA4HTSHRTEAD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5648551-A | CATALYTIC OXIDATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-07-15 | — | — | US | disclosed |