SCHEMBL425356

SCHEMBL425356

Cc1ccc(Oc2ccc(Oc3ccccc3)cc2)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.69
SMN1; SMN2 Q16637 1/20 0.69
LTA4H P09960 6/20 0.67
TSHR P16473 2/20 0.67
TEAD4 Q15561 1/20 0.61
TDP1 Q9NUW8 2/20 0.58
ALDH1A1 P00352 1/20 0.58
POLB P06746 1/20 0.58
MAPT P10636 1/20 0.58
NR1H2 P55055 1/20 0.56
BAX Q07812 1/20 0.56
MAOA P21397 1/20 0.56
FFAR1 O14842 1/20 0.56
ACHE P22303 2/20 0.53
LMNA P02545 1/20 0.53
ALOX12 P18054 1/20 0.53
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
MAPK14 Q16539 1/20 0.51
CA1 P00915 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12355 1.00 HTT (0.69) HTTSMN1; SMN2LTA4HTSHRTEAD4
SCHEMBL17081753 1.00 HTT (0.69) HTTSMN1; SMN2LTA4HTSHRTEAD4
Toluene SCHEMBL8854763 0.97 HTT (0.67) HTTSMN1; SMN2LTA4HTSHRTEAD4
Diphenylether SCHEMBL9008689 0.97 LTA4H (0.71) HTTSMN1; SMN2LTA4HTSHRTEAD4
SCHEMBL24322042 0.93 HTT (0.62) HTTSMN1; SMN2LTA4HTSHRTEAD4
Trimethylammonium SCHEMBL27576820 0.93 HTT (0.62) HTTSMN1; SMN2LTA4HTSHRTEAD4
SCHEMBL822790 0.93 HTT (0.62) HTTSMN1; SMN2LTA4HTSHRTEAD4
SCHEMBL20419433 0.93 HTT (0.62) HTTSMN1; SMN2LTA4HTSHRTEAD4
Diphenylether SCHEMBL19206965 0.92 LTA4H (0.71) HTTSMN1; SMN2LTA4HTSHRTEAD4
SCHEMBL16741276 0.91 SMN1; SMN2 (0.60) HTTSMN1; SMN2LTA4HTSHRTEAD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1454891-B1 Process for preparation of 4-(4-phenoxyphenoxy) benzoic acid by oxidation of 1-(4-methylphenoxy)-4-phenoxybenzene GHARDA CHEMICALS LTD (IN) 2005-12-28 EP claimed
EP-1454891-A1 Process for preparation of 4-(4-phenoxyphenoxy) benzoic acid by oxidation of 1-(4-methylphenoxy)-4-phenoxybenzene Gharda Chemicals Limited (IN) 2004-09-08 EP claimed
US-11206825-B2 Grease-like gel for repelling insects and preventing undesirable behavior in hoofed animals PACIFIC TECH INDUSTRIES, INC. (US) 2021-12-28 US disclosed
US-11191267-B2 Grease-like gel for repelling rodents PACIFIC TECH INDUSTRIES, INC. (US) 2021-12-07 US disclosed
WO-2021219889-A1 INSULATED CONDUCTOR FOR USE IN A WINDING, WINDING DERIVED THEREFROM AND CORRESPONDING MANUFACTURING METHODS ARKEMA FRANCE (FR) 2021-11-04 WO disclosed
US-11111358-B2 Stabilizer compounds SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2021-09-07 US disclosed
US-11111215-B2 Piperidine-based stabilizers and polymers end-capped with the same SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2021-09-07 US disclosed
US-10954359-B2 Hydroxybenzophenone-based stabilizers and polymers end-capped with the same SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2021-03-23 US disclosed
US-20200337300-A1 GREASE-LIKE GEL FOR REPELLING INSECTS AND PREVENTING UNDESIRABLE BEHAVIOR IN HOOFED ANIMALS PACIFIC TECH INDUSTRIES, INC. 2020-10-29 US disclosed
US-20200267976-A1 GREASE-LIKE GEL FOR REPELLING RODENTS PACIFIC TECH INDUSTRIES INC (US) 2020-08-27 US disclosed
US-20200157312-A1 STABILIZER COMPOUNDS SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2020-05-21 US disclosed
EP-0120036-A1 BORON-CONTAINING HETEROCYCLIC COMPOUNDS AND LUBRICATING OILS CONTAINING SAME UNION OIL COMPANY OF CALIFORNIA (US) 1984-10-03 EP disclosed
WO-1984001169-A1 BORON-CONTAINING HETEROCYCLIC COMPOUNDS AND LUBRICATING OILS CONTAINING SAME UNION OIL CO (US) 1984-03-29 WO disclosed
US-4427560-A BIS/DITHIOBEZIL/ METAL DERIVATIVE AND A POLYSULFIDE DERIVATIVE OF 2,5-DIMERCAPTO-1,3,4-THIADIAZOLE UNION OIL COMPANY OF CALIFORNIA (US) 1984-01-24 US disclosed
US-4412928-A Corrosion inhibitors for boron-containing lubricants UNION OIL COMPANY OF CALIFORNIA (US) 1983-11-01 US disclosed
US-4410436-A TEREPHTHALIC ACID, POLYSULFIDE DERIVATIVE OF 2,5-DIMERCAPTO-1,3,4- THIADIAZOLE UNION OIL COMPANY OF CALIFORNIA (US) 1983-10-18 US disclosed
US-4400284-A Boron derivatives as lubricant additives UNION OIL COMPANY OF CALIFORNIA (US) 1983-08-23 US disclosed
US-4218331-A SPERM OIL SUBSTITUTE GULF RESEARCH & DEVELOPMENT COMPANY (US) 1980-08-19 US disclosed
US-4136042-A EXTREME PRESSURE LUBRICANTS GULF RESEARCH & DEVELOPMENT COMPANY (US) 1979-01-23 US disclosed
US-4113782-A CATALYTIC OXIDATION AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1978-09-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200157312-A1 STABILIZER COMPOUNDS HSF1, HEATR1, TBCA HTT 318/4885SMN1; SMN2 590/4885LTA4H 2768/4885
US-11206825-B2 Grease-like gel for repelling insects and preventing undesirable behavior in hoofed animals WAPL, HPN, CAT HTT 1605/4885SMN1; SMN2 2691/4885LTA4H 892/4885
US-11191267-B2 Grease-like gel for repelling rodents MGLL, TGM3, GSTO1 HTT 3512/4885SMN1; SMN2 2792/4885LTA4H 357/4885
US-20200337300-A1 GREASE-LIKE GEL FOR REPELLING INSECTS AND PREVENTING UNDESIRABLE BEHAVIOR IN HOOFED ANIMALS WAPL, HPN, CAT HTT 1605/4885SMN1; SMN2 2691/4885LTA4H 892/4885
US-20200267976-A1 GREASE-LIKE GEL FOR REPELLING RODENTS MGLL, TGM3, GSTO1 HTT 3512/4885SMN1; SMN2 2792/4885LTA4H 357/4885
US-10954359-B2 Hydroxybenzophenone-based stabilizers and polymers end-capped with the same TYR, HSPA1B, HSPH1 HTT 18/4885SMN1; SMN2 3109/4885LTA4H 1723/4885
US-11111358-B2 Stabilizer compounds HSF1, HEATR1, TBCA HTT 318/4885SMN1; SMN2 590/4885LTA4H 2768/4885
US-11111215-B2 Piperidine-based stabilizers and polymers end-capped with the same CAPZA1, UNG, CAPZA2 HTT 247/4885SMN1; SMN2 1724/4885LTA4H 2578/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.