Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAM | P19021 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8854975 | 1.00 | PAM (0.58) | PAMMAOBALOX5MEN1KMT2A | |
| SCHEMBL23064569 | 0.84 | PAM (0.63) | PAMMAOBALOX5MEN1KMT2A | |
| SCHEMBL2435015 | 0.84 | GSK3B (0.53) | MAOBALOX5NPC1ALDH1A1 | |
| SCHEMBL2435018 | 0.84 | GSK3B (0.53) | MAOBALOX5NPC1ALDH1A1 | |
| SCHEMBL2877458 | 0.77 | CYP4F2 (0.64) | PAMMAOBMEN1KMT2AMAOA | |
| SCHEMBL2877454 | 0.77 | CYP4F2 (0.64) | PAMMAOBMEN1KMT2AMAOA | |
| SCHEMBL10891880 | 0.76 | PAM (0.61) | PAMMAOBMEN1KMT2AMAOA | |
| SCHEMBL10891882 | 0.76 | PAM (0.61) | PAMMAOBMEN1KMT2AMAOA | |
| SCHEMBL22024170 | 0.75 | NPC1 (0.61) | MAOBALOX5MEN1KMT2ANPC1 | |
| SCHEMBL7373222 | 0.75 | NPC1 (0.61) | MAOBALOX5MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599952-A | A 4-FLUOROBIPHENYL DERIVATIVE | FUJIREBIO INC. (JP) | 1997-02-04 | — | — | US | disclosed |
| US-5481009-A | Methods of producing carboxylic acid ester derivatives and intermediates for use in the methods | FUJIREBIO INC. (JP) | 1996-01-02 | — | — | US | disclosed |
| EP-0643054-A2 | Methods of producing carboxylic acid ester derivatives and intermediates for use in the methods | FUJIREBIO Inc. (JP) | 1995-03-15 | — | — | EP | disclosed |
| EP-0633242-A1 | Heptanoate derivatives | FUJIREBIO Inc. (JP) | 1995-01-11 | — | — | EP | disclosed |