SCHEMBL8855

SCHEMBL8855

[C]1C=Cc2ccccc2N1

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.48
MAPT P10636 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1162635 0.75
SCHEMBL207759 0.68 GAA (0.44) GAAMAPT
SCHEMBL208462 0.68 GAA (0.44) GAAMAPT
SCHEMBL55652 0.67 GAA (0.43) GAAMAPT
SCHEMBL210283 0.67 GAA (0.43) GAAMAPT
SCHEMBL6198503 0.67 MAPT (0.48) GAAMAPT
Iminostilbene SCHEMBL75288 0.66 MAPT (1.00) GAAMAPT
Iminostilbene SCHEMBL29926907 0.66 MAPT (1.00) GAAMAPT
SCHEMBL4962550 0.66 AXL (0.31)
SCHEMBL663013 0.64 GAA (0.40) GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 12976 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240228501-A1 IMIDAZOLE-CONTAINING CONDENSED RING DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF IN MEDICINE CHANGCHUN GENESCIENCE PHARMACEUTICAL CO., LTD. (CN) 2024-07-11 US claimed
WO-2024126648-A1 SULFOXIMINES AS INHIBITORS OF NaV1.8 Grünenthal GmbH (DE) 2024-06-20 WO claimed
EP-4385980-A1 INDAZOLES AS INHIBITORS OF NAV1.8 Grünenthal GmbH (DE) 2024-06-19 EP claimed
EP-4385979-A1 MULTICYCLIC INHIBITORS OF NAV1.8 Grünenthal GmbH (DE) 2024-06-19 EP claimed
EP-4385984-A1 PYRIDINE-N-OXIDES AS INHIBITORS OF NAV1.8 Grünenthal GmbH (DE) 2024-06-19 EP claimed
US-20240139191-A1 SMALL MOLECULES AS LARP1 LIGANDS UNIVERSITY OF PITTSBURGH -OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2024-05-02 US claimed
WO-2024067560-A1 SULFONAMIDE COMPOUND AND MEDICAL USE THEREOF 中国药科大学 2024-04-04 WO claimed
WO-2024071629-A1 NOVEL FLUORENE DERIVATIVE COMPOUND AND USE THEREOF (주)제이디바이오사이언스 2024-04-04 WO claimed
CN-117682973-A Sulfonamide compound and medical application thereof 中国药科大学 2024-03-12 CN claimed
CN-111138301-B Biphenyl compound, intermediate, preparation method, pharmaceutical composition and application 上海再极医药科技有限公司 2024-01-05 CN claimed
EP-0297871-A2 Novel polymethine dyes and UV absorbers and imaging materials for their use EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1989-01-04 EP claimed
US-4698352-A 4-oxo-1,4-dihydronicotinic acid derivatives, salts thereof, and antibacterial agents containing the same TOYAMA CHEMICAL CO., LTD. (JP) 1987-10-06 US claimed
US-4687853-A COLOR FORMERS BAYER AKTIENGESELLSCHAFT, A CORP OF GERMANY (DE) 1987-08-18 US claimed
US-4604380-A ADMINISTERING TO TREAT BACTERIAL OR MYCOPLASMAL INFECTION ELI LILLY AND COMPANY (US) 1986-08-05 US claimed
EP-0014402-B1 NOVEL 20-0-ACYLMAYTANSINOIDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Takeda Chemical Industries, Ltd. (JP) 1983-07-20 EP claimed
US-4307016-A FUNGICIDES, PROTOZOACIDES OR ANTITUMOR AGENTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1981-12-22 US claimed
US-4294757-A BLEACHING CELLULOSE FIBERS AND ADDITION OF ALKALI METAL POLYPHOSPHATES AND ALKALI METAL DIETHYLENETRIAMINE PENTA(METHYLENE PHOSPHONAT) TAKEDA CHEMICAL INDUSTRIES, LTD (JP) 1981-10-13 US claimed
US-4256746-A ANTITUMOR AGENTS; MICROBIOCIDES; MITOSIS TAKEDA CHEMICAL INDUSTRIES (JP) 1981-03-17 US claimed
US-4175956-A Electrophotosensitive materials for migration imaging processes EASTMAN KODAK COMPANY (US) 1979-11-27 US claimed
US-4113867-A ANTHELMINTICS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1978-09-12 US claimed