Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8855 | 0.68 | GAA (0.48) | GAAMAPT | |
| SCHEMBL20958405 | 0.65 | GAA (0.50) | GAAMAPT | |
| SCHEMBL6198503 | 0.64 | MAPT (0.48) | GAAMAPT | |
| SCHEMBL210283 | 0.64 | GAA (0.43) | GAAMAPT | |
| SCHEMBL206343 | 0.64 | GAA (0.33) | GAAMAPT | |
| SCHEMBL34259 | 0.64 | GAA (0.48) | GAAMAPT | |
| Iminostilbene SCHEMBL75288 | 0.63 | MAPT (1.00) | GAAMAPT | |
| Iminostilbene SCHEMBL29926907 | 0.63 | MAPT (1.00) | GAAMAPT | |
| SCHEMBL8654087 | 0.62 | GAA (0.46) | GAAMAPT | |
| Iodide SCHEMBL12466756 | 0.62 | GAA (0.46) | GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1301 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016518-A1 | HETEROCYCLIC DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF | 四川海思科制药有限公司 | 2023-02-16 | — | — | WO | claimed |
| CN-113861188-A | Pyrazolo [3,4-b ] pyridine derivative, preparation method thereof and application thereof as HPK1 inhibitor | 杭州医学院 | 2021-12-31 | — | — | CN | claimed |
| CN-113105420-A | Fused ring arylamine compound, application thereof and organic electroluminescent device containing compound | 浙江虹舞科技有限公司 | 2021-07-13 | — | — | CN | claimed |
| US-20210198235-A1 | DERIVATIVES OF PIPERLONGUMINE AND USES THEREOF | AURANSA INC. | 2021-07-01 | — | — | US | claimed |
| WO-2021123883-A1 | MACROCYCLIC AMIDES ACTING AS PLASMEPSIN INHBITORS FOR THE TREATMENT OF MALARIA | LATVIAN INSTITUTE OF ORGANIC SYNTHESIS (LV) | 2021-06-24 | — | — | WO | claimed |
| CN-112939788-A | Amantadine compound, application thereof and organic electroluminescent device containing amantadine compound | 浙江虹舞科技有限公司 | 2021-06-11 | — | — | CN | claimed |
| WO-2021001697-A1 | NOVEL BORONIC ACID CONTAINING PEPTIDOMIMETICS AS MALARIAL SERINE PROTEASE INHIBITORS | LATVIAN INSTITUTE OF ORGANIC SYNTHESIS (LV) | 2021-01-07 | — | — | WO | claimed |
| WO-2019103897-A1 | DERIVATIVES OF PIPERLONGUMINE AND USES THEREOF | AURANSA INC. (US) | 2019-05-31 | — | — | WO | claimed |
| US-20180072758-A1 | 5HT3 RECEPTOR ANTAGONISTS | TAKEDA CALIFORNIA, INC. | 2018-03-15 | — | — | US | claimed |
| WO-2017069601-A1 | SUBSTITUTED AMINOALKYLAZOLES AS MALARIAL ASPARTIC PROTEASE INHIBITORS | LATVIAN INSTITUTE OF ORGANIC SYNTHESIS (LV) | 2017-04-27 | — | — | WO | claimed |
| EP-0848000-A1 | Pharmaceutical pyridine derivatives, processes for preparing the same and intermediates therefor | TANABE SEIYAKU CO., LTD. (JP) | 1998-06-17 | — | — | EP | claimed |
| EP-0748805-B1 | Naphthalene derivatives, process for the preparation thereof, and intermediates therefor, and pharmaceutical compositions comprising them | TANABE SEIYAKU CO (JP) | 1998-04-08 | — | — | EP | claimed |
| WO-1997008155-A1 | NOVEL 2,3-DIOXO-1,2,3,4-TETRAHYDRO-QUINOYXALINYL DERIVATIVES | NOVARTIS AG (CH) | 1997-03-06 | — | — | WO | claimed |
| EP-0748805-A1 | Naphthalene derivatives, process for the preparation thereof, and intermediates therefor, and pharmaceutical compositions comprising them | TANABE SEIYAKU CO., LTD. (JP) | 1996-12-18 | — | — | EP | claimed |
| CN-1033453-C | Pyridylthiazolidine carboxylic acid amide derivative and its preparing method | SANKYO CO (JP) | 1996-12-04 | — | — | CN | claimed |
| US-5576321-A | ALKOXY-SUBSTITUTED INDOLES | ELI LILLY AND COMPANY (US) | 1996-11-19 | — | — | US | claimed |
| WO-1996022290-A1 | COMPOUNDS HAVING EFFECTS ON SEROTONIN-RELATED SYSTEMS | ELI LILLY AND COMPANY (US) | 1996-07-25 | — | — | WO | claimed |
| EP-0722941-A2 | Compounds having effects on serotonin-related systems | ELI LILLY AND COMPANY (US) | 1996-07-24 | — | — | EP | claimed |
| CN-1074682-A | Pyridylthiazolidine carboxylic acid amide derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 1993-07-28 | — | — | CN | claimed |
| CN-1039810-A | ALPHA-ADRENERGIC RECEPTOR ANTAGONISTS | SMITHKLINE BECKMAN CORP (US) | 1990-02-21 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210198235-A1 | DERIVATIVES OF PIPERLONGUMINE AND USES THEREOF | THPO, PIR, PAK6 | GAA 3618/4885MAPT 2532/4885 |
| US-20180072758-A1 | 5HT3 RECEPTOR ANTAGONISTS | HTR3A, HTR3B, HTR5A | GAA 1767/4885MAPT 1056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.