SCHEMBL8855243

SCHEMBL8855243

c1csc(CNc2ncc3[nH]cnc3n2)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.54
LMNA P02545 1/20 0.54
CDK2 P24941 3/20 0.51
CDK1 P06493 2/20 0.50
CCNB1 P14635 2/20 0.50
CCNB2 O95067 1/20 0.50
CCNA2 P20248 1/20 0.50
CCNA1 P78396 1/20 0.50
CCNB3 Q8WWL7 1/20 0.50
HDAC3 O15379 1/20 0.47
HDAC1 Q13547 1/20 0.47
HDAC2 Q92769 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
KCNH3 Q9ULD8 2/20 0.44
PAK1 Q13153 1/20 0.43
POLA1 P09884 1/20 0.43
CCNT1 O60563 1/20 0.41
CDK7 P50613 1/20 0.41
CDK9 P50750 1/20 0.41
CCNH P51946 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4411497 0.80 SMN1; SMN2 (0.49) SMN1; SMN2LMNACDK2CDK1CCNB1
SCHEMBL16171 0.77 CDK2 (0.64) LMNACDK2CDK1CCNB1HDAC3
SCHEMBL15693 0.77 SMN1; SMN2 (0.55) SMN1; SMN2LMNACDK2CDK1CCNB1
SCHEMBL10644637 0.73 ALDH1A1 (0.55) SMN1; SMN2LMNACDK2CDK1CCNB1
SCHEMBL27873803 0.71 KCNH3 (0.51) SMN1; SMN2LMNAHDAC3HDAC1HDAC2
SCHEMBL22191610 0.71 HDAC3 (0.61) SMN1; SMN2LMNAHDAC3HDAC1HDAC2
2-Aminopurine SCHEMBL28048761 0.71 ALDH1A1 (0.59) LMNACDK2CDK1CCNB1CCNA2
SCHEMBL29564111 0.71 CDK2 (0.49) LMNACDK2CDK1CCNB1CCNB2
SCHEMBL27114180 0.71 CLK4 (0.43) SMN1; SMN2LMNACDK2ALDH1A1UTS2R
SCHEMBL5934362 0.71 POLA1 (0.54) CDK2CDK1CCNB1PAK1POLA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5654255-A MIXTURE OF A N,N-DIMETHYLPIPERIDINIUM SALT, HEXITOL AND CYTOKININ; COTTON PLANTS BASF CORPORATION (US) 1997-08-05 US claimed
US-4718936-A PLANT GROWTH REGULATORS BASF AKTIENGESELLSCHAFT (DE) 1988-01-12 US disclosed
EP-0154937-A2 6-(3-Thienylmethylamino)-purin, process for its preparation and its use BASF Aktiengesellschaft (DE) 1985-09-18 EP disclosed