Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 15/20 | 0.82 |
| ▸ | ADRB3 | P13945 | 7/20 | 0.70 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.70 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.66 |
| ▸ | HTR1A | P08908 | 1/20 | 0.66 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ractopamine SCHEMBL28884309 | 0.92 | ADRB2 (0.91) | ADRB2ADRB3ADRB1SLC6A4ADRA1A | |
| Butopamine SCHEMBL122463 | 0.91 | ADRB2 (1.00) | ADRB2ADRB3ADRB1SLC6A4ADRA1A | |
| Ractopamine SCHEMBL10659583 | 0.91 | ADRB2 (1.00) | ADRB2ADRB3ADRB1SLC6A4ADRA1A | |
| Ractopamine SCHEMBL144797 | 0.91 | ADRB2 (1.00) | ADRB2ADRB3ADRB1SLC6A4ADRA1A | |
| Ractopamine SCHEMBL9757702 | 0.91 | ADRB2 (1.00) | ADRB2ADRB3ADRB1SLC6A4ADRA1A | |
| Butopamine SCHEMBL351104 | 0.89 | ADRB2 (0.97) | ADRB2ADRB3ADRB1SLC6A4ADRA1A | |
| Ractopamine SCHEMBL11471317 | 0.89 | ADRB2 (0.97) | ADRB2ADRB3ADRB1SLC6A4ADRA1A | |
| Ractopamine SCHEMBL350754 | 0.89 | ADRB2 (0.97) | ADRB2ADRB3ADRB1SLC6A4ADRA1A | |
| Butopamine SCHEMBL11471316 | 0.89 | ADRB2 (0.97) | ADRB2ADRB3ADRB1SLC6A4ADRA1A | |
| Ractopamine SCHEMBL8892153 | 0.89 | ADRB2 (0.97) | ADRB2ADRB3ADRB1SLC6A4ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691385-A | PHENETHANOLAMINES | ELI LILLY AND COMPANY (US) | 1997-11-25 | — | — | US | disclosed |
| US-5643967-A | ANIMAL GROWTH REGULATORS OF BETA-PHENETHANOLAMINES FOR FEED EFFICIENCY | ELI LILLY AND COMPANY (US) | 1997-07-01 | — | — | US | disclosed |
| US-5631298-A | B-PHENETHANOLAMINES | ELI LILLY AND COMPANY (US) | 1997-05-20 | — | — | US | disclosed |
| US-4992473-A | Beta-phenethanolamines | ELI LILLY AND COMPANY (US) | 1991-02-12 | — | — | US | disclosed |
| US-4849453-A | ANIMAL GROWTH REGULATORS | ELI LILLY AND COMPANY (US) | 1989-07-18 | — | — | US | disclosed |
| EP-0117647-B1 | IMPROVEMENTS IN OR RELATING TO PHENETHANOLAMINES | ELI LILLY AND COMPANY (US) | 1988-08-17 | — | — | EP | disclosed |
| US-4734437-A | PHENETHANOLAMINES | ELI LILLY AND COMPANY (US) | 1988-03-29 | — | — | US | disclosed |
| US-4690951-A | B-PHENETHANGLAMINES; FEED EFFICIENCY AND LEANESS | ELI LILLY AND COMPANY (US) | 1987-09-01 | — | — | US | disclosed |
| EP-0117647-A1 | Improvements in or relating to phenethanolamines | ELI LILLY AND COMPANY (US) | 1984-09-05 | — | — | EP | disclosed |